Molecular structure of 13,14-Dihydro-15-keto-prostaglandin F2α, CAS Number: 27376-76-7
13,14-Dihydro-15-keto-prostaglandin F2α (CAS 27376-76-7)
Alternate Names:
13,14-Dihydro-15-oxoprostaglandin F; PGFM
Application:
13,14-Dihydro-15-keto-prostaglandin F2α is a metabolite of PGF2α shown to bind bovine acetylcholine esterase
CAS Number:
27376-76-7
Purity:
≥95%
Molecular Weight:
354.48
Molecular Formula:
C20H34O5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
13,14-Dihydro-15-keto-prostaglandin F2α is a metabolite of prostaglandin F2α, and is used extensively as a tool in research to understand the mechanisms of inflammation. This compound is often used in biological studies for assessing the extent of the body′s inflammatory response, due to its presence following the breakdown of prostaglandin F2α. In research focused on physiology, 13,14-Dihydro-15-keto-prostaglandin F2α is of particular interest for its role in functions including the regulation of the estrous cycle and parturition. Additionally, it serves as an important compound for studying the pathophysiology of conditions where prostaglandin metabolism is disrupted or altered.
13,14-Dihydro-15-keto-prostaglandin F2α (CAS 27376-76-7) References
- A quantitative solid-phase enzymeimmunoassay for 13,14-dihydro-15-keto- prostaglandin F2 alpha in plasma. | Del Vecchio, RP., et al. 1992. Prostaglandins. 43: 321-30. PMID: 1609119
- 15-hydroxyprostaglandin dehydrogenase. A review. | Hansen, HS. 1976. Prostaglandins. 12: 647-79. PMID: 184496
- 13,14-Dihydro-15-keto prostaglandin F2α release in response to oxytocin challenge early post-partum in anoestrous Nelore cows submitted to temporary calf removal and progesterone priming. | Satrapa, RA., et al. 2010. Reprod Domest Anim. 45: 881-7. PMID: 19392666
- Using PGFM (13,14-dihydro-15-keto-prostaglandin F2α) as a non-invasive pregnancy marker for felids. | Dehnhard, M., et al. 2012. Theriogenology. 77: 1088-99. PMID: 22192399
- Effects of tylosin, tilmicosin and tulathromycin on inflammatory mediators in bronchoalveolar lavage fluid of lipopolysaccharide-induced lung injury. | Er, A. and Yazar, E. 2012. Acta Vet Hung. 60: 465-76. PMID: 23160029
- A biotin-streptavidin amplified enzymeimmunoassay for 13,14-dihydro-15-keto-PGF2 alpha. | Meyer, HH., et al. 1989. Prostaglandins. 38: 375-83. PMID: 2675197
- Use of urinary 13,14, dihydro-15-keto-prostaglandin F2α (PGFM) concentrations to diagnose pregnancy and predict parturition in the giant panda (Ailuropoda melanolecua). | Roberts, BM., et al. 2018. PLoS One. 13: e0195599. PMID: 29718929
- Relationship of vaginal discharge characteristics evaluated by Metricheck device to metabolic status in postpartum dairy cows. | Kawashima, C., et al. 2018. Reprod Domest Anim. 53: 1396-1404. PMID: 30051632
- Assessment of peripheral markers and ultrasonographic parameters in pregnant mares receiving intramuscular or intrauterine cloprostenol. | Podico, G., et al. 2020. Theriogenology. 142: 77-84. PMID: 31581046
- Multi-Omics Approach Points to the Importance of Oxylipins Metabolism in Early-Stage Breast Cancer. | Chistyakov, DV., et al. 2022. Cancers (Basel). 14: PMID: 35454947
- Conditions of the cervix for the increase of plasma levels of 13,14-dihydro-15-keto-prostaglandin F2 alpha after amniotomy at term. | Manabe, Y., et al. 1987. Prostaglandins. 33: 757-66. PMID: 3588976
- Changes in the C-reactive protein and 13,14-dihydro-15-keto-prostaglandin F2α concentrations of uterine lavage samples after the administration of povidone-iodine in cows. | Ando, Y., et al. 2022. J Vet Med Sci. 84: 1373-1376. PMID: 35934787
- Effect of route of administration of dinoprost tromethamine on plasma profiles of 13,14-dihydro-15-keto-prostaglandin F2α and progesterone in lactating Holstein cows. | Mezera, MA., et al. 2021. JDS Commun. 2: 421-425. PMID: 36337114
- Prostaglandins and thromboxanes. | Samuelsson, B. 1978. Recent Prog Horm Res. 34: 239-58. PMID: 366681
- Atretic preovulatory follicles could be precursors of ovarian lutein cysts in the pig. | Ziecik, AJ., et al. 2023. Sci Rep. 13: 7758. PMID: 37173342
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
13,14-Dihydro-15-keto-prostaglandin F2α, 1 mg | sc-201236 | 1 mg | $103.00 | |||
13,14-Dihydro-15-keto-prostaglandin F2α, 10 mg | sc-201236A | 10 mg | $546.00 |