13,14-dihydro-15-keto Prostaglandin E1-d4
Alternate Names:
13,14-dh-15-k PGE1-d4
Molecular Weight:
358.5
Molecular Formula:
C20H30O5D4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Contains four deuterium atoms at the 3, 3′, 4, and 4′ positions. Intended for use as an internal standard for the quantification of 13,14-dh-15-k PGE1 by GC- or LC-mass spectrometry. A metabolite of PGE1 with much reduced biological activity.1,2,3 Steady state plasma concentrations are about 10 pg/ml.1 A weak inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 54 and 200 µM.
13,14-dihydro-15-keto Prostaglandin E1-d4 References
- On the metabolism of prostaglandin E1 administered intravenously to human volunteers. | Peskar, BA., et al. 1991. J Physiol Pharmacol. 42: 327-31. PMID: 1793892
- On the metabolism of prostaglandins E 1 and E 2 in man. | Hamberg, M. and Samuelsson, B. 1971. J Biol Chem. 246: 6713-21. PMID: 5126221
- Comparison of the inhibitory effect of E-prostaglandins in human and rabbit platelet-rich plasma and washed platelets. | Kobzar, G., et al. 1993. Comp Biochem Physiol C Comp Pharmacol Toxicol. 106: 489-94. PMID: 7904921
- In vivo formation of prostaglandin E1 and prostaglandin E2 in atopic dermatitis. | Leonhardt, A., et al. 1997. Br J Dermatol. 136: 337-40. PMID: 9115911
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
13,14-dihydro-15-keto Prostaglandin E1-d4, 25 µg | sc-220596 | 25 µg | $105.00 | |||
13,14-dihydro-15-keto Prostaglandin E1-d4, 50 µg | sc-220596A | 50 µg | $200.00 |