Date published: 2025-12-15

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12-(7-Nitrobenzofurazan-4-ylamino)dodecanoic acid (CAS 96801-39-7)

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Alternate Names:
NBD-C12 acid; 12-(7-Nitro-2,1,3-benzoxadiazol-4-ylamino)dodecanoic acid
Application:
12-(7-Nitrobenzofurazan-4-ylamino)dodecanoic acid is an amine-reactive, fluorescent fatty acid analog
CAS Number:
96801-39-7
Purity:
≥95%
Molecular Weight:
378.42
Molecular Formula:
C18H26N4O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-(7-Nitrobenzofurazan-4-ylamino)dodecanoic acid functions as a fluorescent probe in biochemical and biophysical studies. It is used to label and track proteins, peptides, and other biomolecules in various experimental applications. The mechanism of action involves the covalent attachment of the compound to specific amino acid residues within the target biomolecule, allowing for the visualization and quantification of protein-protein interactions, conformational changes, and enzymatic activities. The fluorescent properties of the compound enables monitoring and analyzing the behavior and dynamics of the labeled biomolecules in real-time, providing insights into their function and structure. Additionally, the 2-(7-Nitrobenzofurazan-4-ylamino)dodecanoic acid′s ability to undergo specific chemical reactions with target biomolecules makes it useful for studying various biological processes at the molecular level.


12-(7-Nitrobenzofurazan-4-ylamino)dodecanoic acid (CAS 96801-39-7) References

  1. Sensitive assay for hormone-sensitive lipase using NBD-labeled monoacylglycerol to detect low activities in rat adipocytes.  |  Petry, S., et al. 2005. J Lipid Res. 46: 603-14. PMID: 15627655
  2. Hydrophilic polymer matrices in optical array sensing.  |  Anzenbacher, P., et al. 2010. Curr Opin Chem Biol. 14: 693-704. PMID: 20817542
  3. Synthesis and Bioevaluation of Macrocycle-Polyamine Conjugates as Cell Migration Inhibitors.  |  Skruber, K., et al. 2017. J Med Chem. 60: 8606-8619. PMID: 28976754
  4. Spastin tethers lipid droplets to peroxisomes and directs fatty acid trafficking through ESCRT-III.  |  Chang, CL., et al. 2019. J Cell Biol. 218: 2583-2599. PMID: 31227594
  5. Targeting COX-1 by mofezolac-based fluorescent probes for ovarian cancer detection.  |  Scilimati, A., et al. 2019. Eur J Med Chem. 179: 16-25. PMID: 31229884

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

12-(7-Nitrobenzofurazan-4-ylamino)dodecanoic acid, 100 mg

sc-213594
100 mg
$257.00