Molecular structure of 11β-Prostaglandin E2, CAS Number: 38310-90-6
11β-Prostaglandin E2 (CAS 38310-90-6)
Alternate Names:
9-oxo-11β,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid; 11β-PGE2; 11-epi PGE2
Application:
11β-Prostaglandin E2 is an epimer of PGE2 shown to moderately inhibit PGE2 binding to rat hypothalamic membranes
CAS Number:
38310-90-6
Molecular Weight:
352.5
Molecular Formula:
C20H32O5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
11β-Prostaglandin E2 is the C-11 epimer of PGE2 (sc-201225) and is a moderate inhibitor of PGE2 binding to rat hypothalamic membranes with a Ki = 53 nM. 11β-Prostaglandin E2 may act to stimulate bone resorption in rats and to inhibit PGE2 binding to the prostaglandin transporter protein Ki = 56 nM. These prostaglandin analogues are integral for structure-activity studies used in the deconvolution of these complex biochemical pathways.
11β-Prostaglandin E2 (CAS 38310-90-6) References
- Role of conserved transmembrane cationic amino acids in the prostaglandin transporter PGT. | Chan, BS., et al. 2002. Biochemistry. 41: 9215-21. PMID: 12119036
- Effect of alterations in the cyclopentane ring on bone resorptive activity of prostaglandin. | Raisz, LG. and Woodiel, FN. 1989. Prostaglandins. 37: 229-35. PMID: 2727307
- Prostaglandins of the E series inhibit release of noradrenaline in rat hypothalamus by a mechanism unrelated to classical alpha 2 adrenergic presynaptic inhibition. | Dray, F. and Heaulme, M. 1984. Neuropharmacology. 23: 457-62. PMID: 6145117
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
11β-Prostaglandin E2, 500 µg | sc-223155 | 500 µg | $32.00 | |||
11β-Prostaglandin E2, 1 mg | sc-223155A | 1 mg | $60.00 |