11β-Hydroxy Etiocholanolone (CAS 739-26-4)
Alternate Names:
(3α,5β,11β)-3,11-Dihydroxyandrostan-17-one
CAS Number:
739-26-4
Molecular Weight:
306.44
Molecular Formula:
C19H30O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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11β-Hydroxy Etiocholanolone is a metabolite of adrenal steroidogenesis and has become a focal point in endocrinology research. In studies exploring the metabolism of steroids, this compound serves as a marker to investigate the enzymatic pathways involved in steroid degradation. Researchers utilize 11β-Hydroxy Etiocholanolone to understand its role in the regulation of hormone levels and homeostasis. Additionally, its potential effects on immune modulation are of interest, as researchers examine how various metabolites of hormones can influence immune system responses. The compound also plays a part in scientific studies looking at the broader implications of steroid hormone metabolism in stress response, as well as in the adaptation of bodily functions to various environmental and physiological changes.
11β-Hydroxy Etiocholanolone (CAS 739-26-4) References
- Mass spectrometry of steroid glucuronide conjugates. I. Electron impact fragmentation of 5alpha-/5beta-androstan-3alpha-ol-17-one glucuronides, 5alpha-estran-3alpha-ol-17-one glucuronide and deuterium-labelled analogues. | Thevis, M., et al. 2001. J Mass Spectrom. 36: 159-68. PMID: 11288198
- Non-invasive assessment of adrenocortical function in the male African elephant (Loxodonta africana) and its relation to musth. | Ganswindt, A., et al. 2003. Gen Comp Endocrinol. 134: 156-66. PMID: 14511986
- Endogenous urinary steroids in premenopausal women with uterine leiomyomas. | Jung, BH., et al. 2004. Int J Gynaecol Obstet. 84: 55-60. PMID: 14698830
- Factors influencing the steroid profile in doping control analysis. | Mareck, U., et al. 2008. J Mass Spectrom. 43: 877-91. PMID: 18570179
- Impaired glucose tolerance and insulin resistance are associated with increased adipose 11beta-hydroxysteroid dehydrogenase type 1 expression and elevated hepatic 5alpha-reductase activity. | Tomlinson, JW., et al. 2008. Diabetes. 57: 2652-60. PMID: 18633104
- Urine ratio of tetrahydrocortisol to tetrahydrodeoxycortisol to screen for the systemic administration of cortisone and hydrocortisone. | Meklat, N., et al. 2009. Forensic Sci Int. 185: e13-7. PMID: 19185436
- Accelerated sample treatment for screening of banned doping substances by GC-MS: ultrasonication versus microwave energy. | Galesio, M., et al. 2011. Anal Bioanal Chem. 399: 861-75. PMID: 21049269
- The use of in vitro technologies and high-resolution/accurate-mass LC-MS to screen for metabolites of 'designer' steroids in the equine. | Clarke, A., et al. 2011. Drug Test Anal. 3: 74-87. PMID: 21322180
- Validation of an enzyme immunoassay for the measurement of faecal glucocorticoid metabolites in Eurasian (Lynx lynx) and Iberian lynx (Lynx pardinus). | Pribbenow, S., et al. 2014. Gen Comp Endocrinol. 206: 166-77. PMID: 25066418
- Specificity of anti-prostate cancer CYP17A1 inhibitors on androgen biosynthesis. | Udhane, SS., et al. 2016. Biochem Biophys Res Commun. 477: 1005-1010. PMID: 27395338
- Modified-Release and Conventional Glucocorticoids and Diurnal Androgen Excretion in Congenital Adrenal Hyperplasia. | Jones, CM., et al. 2017. J Clin Endocrinol Metab. 102: 1797-1806. PMID: 27845856
- Adrenal C11-oxy C21 steroids contribute to the C11-oxy C19 steroid pool via the backdoor pathway in the biosynthesis and metabolism of 21-deoxycortisol and 21-deoxycortisone. | Barnard, L., et al. 2017. J Steroid Biochem Mol Biol. 174: 86-95. PMID: 28774496
- Effects of transdermal administration of testosterone gel on the urinary steroid profile in hypogonadal men: Implications in antidoping analysis. | Iannone, M., et al. 2019. Steroids. 152: 108491. PMID: 31499075
- [The excretion of 17-oxosteroids, pregnanes and testosterone in human urine and the dependency on age and sex (author's transl)]. | Gleispach, H. 1973. Z Klin Chem Klin Biochem. 11: 482-6. PMID: 4804155
- Tetrahydrocortisol metabolism in man. | Bradlow, HL., et al. 1968. Steroids. 12: 303-8. PMID: 5674522
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
11β-Hydroxy Etiocholanolone, 10 mg | sc-490219 | 10 mg | $380.00 |