11-trans Leukotriene D4 (CAS 79768-40-4)
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Leukotrienes comprise a family of endogenous metabolites of certain fatty acids and are related to thromboxanes and prostaglandins. They are potent eicosanoid lipid mediators that play numerous roles in inflammation, immunological functions and maintaining biological homeostasis. Leukotrienes possess a conjugated triene structure which gives them their name. They are generally isolated from leukocytes and primarily act through specific G protein-coupled receptors.11-trans Leukotriene D4, also known as 11-trans LTD4, is a C-11 double bond isomer of LTD4 that is formed when LTD4 undergoes slow temperature-dependent isomerization to 11-trans LTD4 during storage. This compound retains about 10-25 % of the potency of LTD4 for contraction of guinea pig ileum, trachea and parenchyma compared to LTD4.
11-trans Leukotriene D4 (CAS 79768-40-4) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
11-trans Leukotriene D4, 25 µg | sc-204972 | 25 µg | $176.00 | |||
11-trans Leukotriene D4, 50 µg | sc-204972A | 50 µg | $334.00 |