11(S)-HEDE (CAS 330800-90-3)

11(S)-HEDE, or 11(S)-hydroxyeicosadienoic acid, with the CAS number 330800-90-3, is a bioactive metabolite derived from dihomo-γ-linolenic acid (DGLA), an omega-6 fatty acid. This metabolite is produced enzymatically by the action of lipoxygenase enzymes, which catalyze the insertion of a hydroxyl group at the 11th carbon of the fatty acid chain. The specific (S) configuration in the 11(S)-HEDE indicates the stereochemistry of the hydroxyl group, which is crucial for its biological activity. In research, 11(S)-HEDE is particularly valued for its role in elucidating lipid signaling pathways that regulate various cellular processes. Studies involving this compound often focus on its interactions with cell membranes and receptors, examining how it influences signaling cascades that modify cellular responses to environmental stimuli. By exploring the interactions and effects of 11(S)-HEDE in various cellular models, researchers can gain deeper insights into the complex mechanisms of lipid-mediated cellular regulation. This includes understanding how cells communicate, adapt, and maintain homeostasis in response to changes within their environment. Through such studies, 11(S)-HEDE serves as a critical tool for advancing knowledge in the fields of cellular biology and biochemistry, providing insights into the complex network of lipid signaling.