(+)-11-Nor-Δ9-THC-9-carboxylic acid glucuronide (CAS 1362113-32-3)

(+)-11-Nor-Δ9-THC-9-carboxylic acid glucuronide is a metabolite of tetrahydrocannabinol (THC), the principal psychoactive constituent of cannabis, typically utilized in analytical chemistry for drug monitoring and forensic applications. As a glucuronide conjugate, this compound is a product of the body′s efforts to make THC more water-soluble for excretion, and it can be detected in biological specimens. Its presence is indicative of the recent ingestion of cannabis, and thus it is used in toxicology studies to understand the metabolism and excretion of cannabinoids. Researchers also employ this chemical to calibrate and validate highly sensitive analytical methods, such as liquid chromatography-tandem mass spectrometry, which are essential for accurate and reliable screening in various contexts where the usage of cannabis needs to be monitored. Furthermore, the study of this compound aids in the exploration of the impact of metabolic factors on the pharmacokinetics of substances related to THC, providing insights into how different bodies process cannabinoids.