Molecular structure of 11-deoxy Prostaglandin E2, CAS Number: 35536-53-9
11-deoxy Prostaglandin E2 (CAS 35536-53-9)
Alternate Names:
11-deoxy PGE2
Application:
11-deoxy Prostaglandin E2 is a stable synthetic analog of prostaglandin E2 with powerful bronchoconstrictor effects
CAS Number:
35536-53-9
Purity:
>99%
Molecular Weight:
336.5
Molecular Formula:
C20H32O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
11-deoxy Prostaglandin E2 is a stable, synthetic analog of PGE2 (sc-201225), that has been shown to have powerful bronchoconstrictor effects; contracts human respiratory tract smooth muscle with potencies ranging from 5 to 30 times higher than PGF2α. This is in contrast to the bronchodilation effects produced by PGE2.
11-deoxy Prostaglandin E2 (CAS 35536-53-9) References
- Prostanoid-induced relaxation of precontracted cat ciliary muscle is mediated by EP2 and DP receptors. | Chen, J. and Woodward, DF. 1992. Invest Ophthalmol Vis Sci. 33: 3195-201. PMID: 1328113
- Sodium butyrate inhibits angiogenesis of human intestinal microvascular endothelial cells through COX-2 inhibition. | Ogawa, H., et al. 2003. FEBS Lett. 554: 88-94. PMID: 14596920
- The occurrence of 15-keto-prostaglandins in the red alga Gracilaria verrucosa. | Dang, TH., et al. 2010. Arch Pharm Res. 33: 1325-9. PMID: 20945130
- Prediction of the Human EP1 Receptor Binding Site by Homology Modeling and Molecular Dynamics Simulation. | Zare, B., et al. 2011. Sci Pharm. 79: 793-816. PMID: 22145106
- Prostaglandins and human respiratory tract smooth muscle: structure activity relationship. | Karim, SM., et al. 1980. Adv Prostaglandin Thromboxane Res. 7: 969-80. PMID: 7369062
- Potent contractile actions of prostanoid EP3-receptor agonists on human isolated pulmonary artery. | Qian, YM., et al. 1994. Br J Pharmacol. 113: 369-74. PMID: 7834185
Activator of:
EP1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
11-deoxy Prostaglandin E2, 1 mg | sc-204962 | 1 mg | $104.00 | |||
11-deoxy Prostaglandin E2, 5 mg | sc-204962A | 5 mg | $471.00 |