Molecular structure of 11-Deoxy Cortisol, CAS Number: 152-58-9
11-Deoxy Cortisol (CAS 152-58-9)
Alternate Names:
Cortexolone; Reichsteins substance S
Application:
11-Deoxy Cortisol is aids in glucocorticoid receptor binding.
CAS Number:
152-58-9
Purity:
≥98%
Molecular Weight:
346.46
Molecular Formula:
C21H30O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
11-Deoxy Cortisol aids in glucocorticoid receptor binding. 11-Deoxy Cortisol is a synthetic steroid belonging to the 21-carbon family of steroids. In scientific research, it has been utilized to explore the impact of glucocorticoid receptor agonists on various cellular processes such as proliferation, differentiation, and gene expression. Additionally, studies have employed 11-Deoxy Cortisol to investigate its effects on protein synthesis, degradation, and enzyme activity when interacting with glucocorticoid receptors.
11-Deoxy Cortisol (CAS 152-58-9) References
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- The effect of the corticosteroid hormone cortexolone on the metabolites produced during phenanthrene biotransformation in Cunninghamella elegans. | Lisowska, K., et al. 2006. Chemosphere. 64: 1499-506. PMID: 16504243
- Investigation of the presence of prednisolone in bovine urine. | de Rijke, E., et al. 2014. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 31: 605-13. PMID: 24392764
- Term neonates with infection and shock display high cortisol precursors despite low levels of normal cortisol. | Khashana, A., et al. 2016. Acta Paediatr. 105: 154-8. PMID: 26537554
- Structure-function analysis for the hydroxylation of Δ4 C21-steroids by the myxobacterial CYP260B1. | Salamanca-Pinzon, SG., et al. 2016. FEBS Lett. 590: 1838-51. PMID: 27177597
- Cortisol intermediates and hydrocortisone responsiveness in critical neonatal disease. | Khashana, A., et al. 2017. J Matern Fetal Neonatal Med. 30: 1721-1725. PMID: 27578461
- Characterization of new recombinant 3-ketosteroid-Δ1-dehydrogenases for the biotransformation of steroids. | Wang, X., et al. 2017. Appl Microbiol Biotechnol. 101: 6049-6060. PMID: 28634849
- Serum metabolic profile characteristics of offspring rats before and after birth caused by prenatal caffeine exposure. | Chen, G., et al. 2019. Toxicology. 427: 152302. PMID: 31568846
- Comparative metabolomics analysis of ovarian developmental stages in Macrobrachium nipponense. | Zhang, Y., et al. 2020. Comp Biochem Physiol Part D Genomics Proteomics. 34: 100648. PMID: 32078987
- Metabolomic Profiling of Poor Ovarian Response Identifies Potential Predictive Biomarkers. | Song, H., et al. 2021. Front Endocrinol (Lausanne). 12: 774667. PMID: 34887835
- Mechanism of the regulation of the 1 alpha,25-dihydroxyvitamin D3 receptor in the rat jejunum by glucocorticoids. | Chan, SD., et al. 1984. J Endocrinol. 103: 295-300. PMID: 6094696
- Pituitary function tests: comparison of ACTH and 11-deoxy-cortisol responses in the metyrapone test and with the insulin hypoglycemia test. | Steiner, H., et al. 1994. Exp Clin Endocrinol. 102: 33-8. PMID: 8005206
- Absence of steroid biosynthetic defects in heterozygote individuals for classic 11 beta-hydroxylase deficiency due to a R448H mutation in the CYP11B1 gene. | Rösler, A. and Cohen, H. 1995. J Clin Endocrinol Metab. 80: 3771-3. PMID: 8530633
- Assessment of hypothalamic-pituitary-adrenocortical axis function in dexamethasone treated very low birth weight infants by a single dose metyrapone test and gas chromatographic mass spectrometric determination of urinary steroids. | Wudy, SA., et al. 1995. J Pediatr Endocrinol Metab. 8: 281-6. PMID: 8821906
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
11-Deoxy Cortisol, 1 g | sc-208845 | 1 g | $56.00 |