Molecular structure of 11-deoxy-11-methylene Prostaglandin D2, CAS Number: 100648-29-1
11-deoxy-11-methylene Prostaglandin D2 (CAS 100648-29-1)
Application:
11-deoxy-11-methylene Prostaglandin D2 is a stable isosteric analog of PGD2
CAS Number:
100648-29-1
Molecular Weight:
350.5
Molecular Formula:
C21H34O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
11-deoxy-11-methylene PGD2 is a novel, chemically stable, isosteric analog of PGD2 wherein the 11-keto group is replaced by an exocyclic methylene. In the PGE series, the analogous modification leads to a stable, somewhat less potent agonist which embodies the same uterine stimulant and cervical ripening activities as the parent prostaglandin. However, 11-deoxy-11-methylene PGD2 has been reported by one group to be essentially without agonist activity on human platelets in a DP1 receptor assay. The CRTH2-receptor actions of 11-deoxy-11-methylene PGD2 are not yet reported.
11-deoxy-11-methylene Prostaglandin D,[object Object], (CAS 100648-29-1) References
- Prostaglandin D synthase: structure and function. | Urade, Y. and Hayaishi, O. 2000. Vitam Horm. 58: 89-120. PMID: 10668396
- Low-dose prostaglandin E2 analogue for cervical dilatation prior to pregnancy termination. | Borten, M., et al. 1984. Am J Obstet Gynecol. 150: 561-5. PMID: 6496588
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
11-deoxy-11-methylene Prostaglandin D2, 1 mg | sc-204967 | 1 mg | $114.00 | |||
11-deoxy-11-methylene Prostaglandin D2, 5 mg | sc-204967A | 5 mg | $516.00 |