Molecular structure of 11-Dehydro-TXB2, CAS Number: 67910-12-7
11-Dehydro-TXB2 (CAS 67910-12-7)
Alternate Names:
11-Dehydro-thromboxane B2
Application:
11-Dehydro-TXB2 is a long-lived prominent metabolite and product of infused thromboxane B2
CAS Number:
67910-12-7
Molecular Weight:
368.47
Molecular Formula:
C20H32O6
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
11-dehydro-TXB2 is a long-lived prominent metabolite and product of infused thromboxane B2 (TXB2), the hydration product of biologically active TXA2, in the urine and blood of several species. It is a reliable parameter for measuring thromboxane production in vivo. It is also an appropriate analytical tool for the detection of the phasic release of TXA2 in human circulation that might occur from platelet activation syndromes. It can be detected using radioimmunoassay.
11-Dehydro-TXB2 (CAS 67910-12-7) References
- High dose of inhaled fluticasone reduces high levels of urinary leukotriene E4 in the early morning in mild and moderate nocturnal asthma. | Tanaka, S., et al. 2003. Chest. 124: 1768-73. PMID: 14605047
- Long-lived enzymatic metabolites of thromboxane B2 in the human circulation. | Lawson, JA., et al. 1986. Anal Biochem. 155: 198-205. PMID: 3087234
- 11-Dehydrothromboxane B2: a quantitative index of thromboxane A2 formation in the human circulation. | Catella, F., et al. 1986. Proc Natl Acad Sci U S A. 83: 5861-5. PMID: 3461463
- Tandem mass spectrometric determination of 11-dehydrothromboxane B2, an index metabolite of thromboxane B2 in plasma and urine. | Schweer, H., et al. 1987. Anal Biochem. 164: 156-63. PMID: 3674365
- Identification of 11-dehydro-TXB2 as a suitable parameter for monitoring thromboxane production in the human. | Westlund, P., et al. 1986. Prostaglandins. 31: 929-60. PMID: 3755250
- Functional metagenomic and metabolomics analysis of gut dysbiosis induced by hyperoxia. | Cai, Y., et al. 2023. Front Microbiol. 14: 1197970. PMID: 37840730
- Radioimmunoassay for 11-dehydro-TXB2: a method for monitoring thromboxane production in vivo. | Kumlin, M. and Granström, E. 1986. Prostaglandins. 32: 741-67. PMID: 3823488
- Thromboxane biosynthesis and future events in diabetes: the ASCEND trial. | Petrucci, G., et al. 2024. Eur Heart J. 45: 1355-1367. PMID: 38385506
- Metabolism of thromboxane B2 in man. Identification of twenty urinary metabolites. | Roberts, LJ., et al. 1981. J Biol Chem. 256: 8384-93. PMID: 7263660
- 11-Dehydro thromboxane B2: a reliable parameter of thromboxane A2 production in dogs. | Yamanaka, S., et al. 1993. Prostaglandins. 45: 221-8. PMID: 8484010
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
11-Dehydro-TXB2, 250 µg | sc-201453 | 250 µg | $902.00 |