Date published: 2026-4-24

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10(S),17(S)-DiHDoHE (CAS 871826-47-0)

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Application:
10(S),17(S)-DiHDoHE is a DHA-derived dihydroxy fatty acid with anti-inflammatory properties
CAS Number:
871826-47-0
Purity:
≥98%
Molecular Weight:
360.5
Molecular Formula:
C22H32O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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10(S),17(S)-DiHDoHE, catalogued under CAS number 871826-47-0, is a chemical compound belonging to the class of hydroxyeicosatetraenoic acids, which are metabolites of arachidonic acid. This compound has drawn significant interest in biochemical research due to its involvement in cellular signaling mechanisms. The structure of 10(S),17(S)-DiHDoHE includes hydroxyl groups that are critical in its function as a signaling molecule, influencing various biochemical pathways. In research settings, this compound has been utilized primarily to study its interaction with cellular receptors and enzymes that play pivotal roles in the regulation of intracellular signals. These studies often focus on understanding how 10(S),17(S)-DiHDoHE affects the activity of these proteins, thereby modulating the physiological responses of cells to external stimuli. For example, its role in the regulation of inflammatory responses has been a subject of investigation, where its ability to modulate enzyme activities involved in the metabolism of fatty acids is of particular interest. Additionally, research involving this compound helps explain its potential impact on the signaling pathways that influence cellular processes such as proliferation and apoptosis. Through such studies, 10(S),17(S)-DiHDoHE contributes to a deeper understanding of cellular dynamics and the complex network of signaling pathways.


10(S),17(S)-DiHDoHE (CAS 871826-47-0) References

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  3. Confusion between protectin D1 (PD1) and its isomer protectin DX (PDX). An overview on the dihydroxy-docosatrienes described to date.  |  Balas, L., et al. 2014. Biochimie. 99: 1-7. PMID: 24262603
  4. Effect of polyunsaturated fatty acids and their metabolites on bleomycin-induced cytotoxic action on human neuroblastoma cells in vitro.  |  Polavarapu, S., et al. 2014. PLoS One. 9: e114766. PMID: 25536345
  5. B Cell Activity Is Impaired in Human and Mouse Obesity and Is Responsive to an Essential Fatty Acid upon Murine Influenza Infection.  |  Kosaraju, R., et al. 2017. J Immunol. 198: 4738-4752. PMID: 28500069
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  7. 12/15-Lipoxygenase Regulates IL-33-Induced Eosinophilic Airway Inflammation in Mice.  |  Miyata, J., et al. 2021. Front Immunol. 12: 687192. PMID: 34093589
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

10(S),17(S)-DiHDoHE, 25 µg

sc-204609
25 µg
$214.00

10(S),17(S)-DiHDoHE, 50 µg

sc-204609A
50 µg
$402.00