10-Pyrene-PC (CAS 95864-17-8)

10-Pyrene-PC, a derivative of phosphatidylcholine (PC) containing a pyrene fluorophore, has emerged as a valuable tool in scientific research for its role in studying membrane dynamics and lipid-protein interactions. One significant area of investigation involves utilizing 10-Pyrene-PC as a fluorescent probe to examine lipid bilayer properties, such as fluidity, curvature, and phase transitions. By incorporating 10-Pyrene-PC into model membranes, researchers can monitor changes in fluorescence intensity and polarization, providing insights into membrane organization and lipid packing. Additionally, 10-Pyrene-PC has been employed to investigate lipid-protein interactions, particularly with membrane-associated proteins such as receptors, ion channels, and transporters. Through fluorescence spectroscopy and imaging techniques, researchers can explain the spatial distribution and dynamics of lipid-protein complexes within cellular membranes. Furthermore, the development of 10-Pyrene-PC analogs and derivatives with altered fluorophore properties has expanded its utility in studying specific membrane environments and biological processes. Overall, 10-Pyrene-PC serves as a valuable tool for advancing our understanding of membrane biophysics and molecular mechanisms underlying cellular function, offering insights into potential targets and diagnostic strategies.