Date published: 2026-5-1

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10,11-Dihydrocarbamazepine (CAS 3564-73-6)

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Alternate Names:
10,11-Dihydro-5H-dibenz[b,f]azepine-5-carboxamide
Application:
10,11-Dihydrocarbamazepine is an impurity present in dibenzazepine drug
CAS Number:
3564-73-6
Molecular Weight:
238.28
Molecular Formula:
C15H14N2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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10,11-Dihydrocarbamazepine is an impurity present in dibenzazepine drug. 10,11-Dihydrocarbamazepine is used as internal standard during simultaneous determination of carbamazepine and its active metabolite in plasma by liquid chromatography. It can be used in chemiluminescence method for determination of carbamazepine.


10,11-Dihydrocarbamazepine (CAS 3564-73-6) References

  1. An orthorhombic polymorph of 10,11-dihydrocarbamazepine.  |  Harrison, WT., et al. 2006. Acta Crystallogr C. 62: o240-2. PMID: 16679591
  2. On-line solid-phase extraction of large-volume injections coupled to liquid chromatography-tandem mass spectrometry for the quantitation and confirmation of 14 selected trace organic contaminants in drinking and surface water.  |  Garcia-Ac, A., et al. 2009. J Chromatogr A. 1216: 8518-27. PMID: 19875124
  3. Simultaneous separation and determination (in serum) of phenytoin and carbamazepine and their deuterated analogues by high-performance liquid chromatography--ultraviolet detection for tracer studies.  |  Szabo, GK., et al. 1990. J Chromatogr. 535: 271-7. PMID: 2089056
  4. Development and validation of an enantioselective liquid-chromatography/tandem mass spectrometry method for the separation and quantification of eslicarbazepine acetate, eslicarbazepine, R-licarbazepine and oxcarbazepine in human plasma.  |  Loureiro, AI., et al. 2011. J Chromatogr B Analyt Technol Biomed Life Sci. 879: 2611-8. PMID: 21816689
  5. Methanesulfonic acid salt forms of carbamazepine and 10,11-dihydrocarbamazepine.  |  Eberlin, AR., et al. 2013. Acta Crystallogr C. 69: 1260-6. PMID: 24192169
  6. Transformation of atenolol, metoprolol, and carbamazepine in soils: The identification, quantification, and stability of the transformation products and further implications for the environment.  |  Koba, O., et al. 2016. Environ Pollut. 218: 574-585. PMID: 27514306
  7. Determination of carbamazepine and 12 degradation products in various compartments of an outdoor aquatic mesocosm by reliable analytical methods based on liquid chromatography-tandem mass spectrometry.  |  Daniele, G., et al. 2017. Environ Sci Pollut Res Int. 24: 16893-16904. PMID: 28573566
  8. Polymorphic Phase Transitions in Carbamazepine and 10,11-Dihydrocarbamazepine.  |  Clout, AE., et al. 2018. Chemistry. 24: 13573-13581. PMID: 29979477
  9. Identification of transformation products of carbamazepine in lettuce crops irrigated with Ultraviolet-C treated water.  |  Martínez-Piernas, AB., et al. 2019. Environ Pollut. 247: 1009-1019. PMID: 30823329
  10. Carbamazepine Ozonation Byproducts: Toxicity in Zebrafish (Danio rerio) Embryos and Chemical Stability.  |  Pohl, J., et al. 2020. Environ Sci Technol. 54: 2913-2921. PMID: 31990190
  11. Liquid chromatographic methods for assay of carbamazepine, 10,11-dihydrocarbamazepine, and related compounds in carbamazepine drug substance and tablets.  |  Cyr, TD., et al. 1987. J Assoc Off Anal Chem. 70: 836-40. PMID: 3680120
  12. Carbamazepine, venlafaxine, tramadol, and their main metabolites: Toxicological effects on zebrafish embryos and larvae.  |  Rodrigues, P., et al. 2023. J Hazard Mater. 448: 130909. PMID: 36860067

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

10,11-Dihydrocarbamazepine, 100 mg

sc-223144
100 mg
$92.00