10,11-Dihydro-10-hydroxy carbamazepine (CAS 29331-92-8)
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10,11-Dihydro-10-hydroxy Carbamazepine is an oxcarbazepine (sc-204826) metabolite which induces microsomal enzymes in hepatocytes via sodium channel protein inhibition. Identification techniques such as liquid chromatography-tandem mass spectrometry is used to quantify 10,11-Dihydro-10-hydroxy Carbamazepine in human plasma. In addition, 10,11-Dihydro-10-hydroxy Carbamazepine promotes the release of hippocampal monoamines and produces a dose-dependent inhibition of glutamatergic excitatory postsynaptic potentials (EPSPs) of rat striatum. Furthermore, 10,11-Dihydro-10-hydroxy Carbamazepine reduces calcium ion concentration via a decrease in high-voltage-activated (HVA) Ca2+ currents evoked by membrane depolarization which is independent of dihydropyridine-sensitive channels.
10,11-Dihydro-10-hydroxy carbamazepine (CAS 29331-92-8) References
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- Electrochemical degradation of 10,11-dihydro-10-hydroxy carbamazepine as the main metabolite of carbamazepine. | Mussa, ZH. and Al-Qaim, FF. 2023. Environ Sci Pollut Res Int.. PMID: 36795212
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
10,11-Dihydro-10-hydroxy carbamazepine, 10 mg | sc-206270 | 10 mg | $273.00 | |||
10,11-Dihydro-10-hydroxy carbamazepine, 10 mg | sc-206270-CW | 10 mg | $418.00 |