Date published: 2026-4-27

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1-Thio-β-D-glucose sodium salt (CAS 10593-29-0)

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Alternate Names:
β-D-Thioglucose; 1-β-D-Glucosylthiose; Glucothiose
Application:
1-Thio-β-D-glucose sodium salt is a glucose derivative and carrier molecule for cell uptake of markers, polymers, and nanoparticles
CAS Number:
10593-29-0
Purity:
≥85%
Molecular Weight:
218.20
Molecular Formula:
C6H11O5S•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Thio-β-D-glucose sodium salt functions as a glycosylation inhibitor in development applications. It acts by competitively inhibiting the glycosylation of proteins, interfering with the attachment of sugar molecules to proteins. This disruption of glycosylation processes can be utilized to study the effects of altered protein glycosylation in cellular and molecular biology experiments. 1-Thio-β-D-glucose sodium salt′s ability to inhibit glycosylation may be valuable for studying the role of glycosylation in cellular and molecular biology.


1-Thio-β-D-glucose sodium salt (CAS 10593-29-0) References

  1. Liquid chromatographic determination of 1-adamantanamine and 2-adamantanamine in human plasma after pre-column derivatization with o-phthalaldehyde and 1-thio-beta-D-glucose.  |  Higashi, Y. and Fujii, Y. 2004. J Chromatogr B Analyt Technol Biomed Life Sci. 799: 349-54. PMID: 14670755
  2. Three 1-thio-beta-D-glucopyranosides from the seeds of Afrostyrax lepidophyllus Mildbr.  |  Ngane, AN., et al. 2006. Carbohydr Res. 341: 2799-802. PMID: 17054924
  3. Thioglucose-stabilized gold nanoparticles as a novel platform for colorimetric bioassay based on nanoparticle aggregation.  |  Watanabe, S., et al. 2010. Colloids Surf B Biointerfaces. 81: 570-7. PMID: 20801619
  4. Water soluble heptakis(6-deoxy-6-thio)cyclomaltoheptaose capped gold nanoparticles via metal vapour synthesis: NMR structural characterization and complexation properties.  |  Uccello-Barretta, G., et al. 2011. Carbohydr Res. 346: 753-8. PMID: 21367401
  5. Electrochemical and STM studies of 1-thio-β-D-glucose self-assembled on a Au(111) electrode surface.  |  Kycia, AH., et al. 2011. Langmuir. 27: 13383-9. PMID: 21939277
  6. Periplasmic binding protein-based detection of maltose using liposomes: a new class of biorecognition elements in competitive assays.  |  Edwards, KA. and Baeumner, AJ. 2013. Anal Chem. 85: 2770-8. PMID: 23411612
  7. Synthesis of Biofunctional Janus Particles.  |  Li, B., et al. 2015. Macromol Rapid Commun. 36: 1200-4. PMID: 25858757
  8. Characterization of a Self-Assembled Monolayer of 1-Thio-β-D-Glucose with Electrochemical Surface Enhanced Raman Spectroscopy Using a Nanoparticle Modified Gold Electrode.  |  Smith, SR., et al. 2015. Langmuir. 31: 10076-86. PMID: 26313341
  9. Surface Modification of Polydivinylbenzene Microspheres with a Fluorinated Glycopolymer Using Thiol-Halogen Click Chemistry.  |  Song, W. and Granville, AM. 2016. Methods Mol Biol. 1367: 123-35. PMID: 26537469
  10. Polydimethylsiloxane-Based Giant Glycosylated Polymersomes with Tunable Bacterial Affinity.  |  Martin, L., et al. 2019. Biomacromolecules. 20: 1297-1307. PMID: 30694656
  11. Facile, Versatile Prepolymerization and Postpolymerization Functionalization Approaches for Well-Defined Fluorescent Conjugated Fluorene-Based Glycopolymers  |  Cuihua Xue, Venkat R. R. Donuru, and Haiying Liu. 2006. Macromolecules. 39: 5747–5752.
  12. Synthesis and Lectin Recognition of Glyco Star Polymers Prepared by "Clicking" Thiocarbohydrates onto a Reactive Scaffold  |  Yong Chen, Gaojian Chen, and Martina H. Stenzel*. 2010. Macromolecules. 43: 8109–8114.
  13. Synthesis, chemical characterization and preliminary in vitro antitumor activity evaluation of new ruthenium(II) complexes with sugar derivatives  |  Gianfranco Fontana a, Michele Abbate b, Girolamo Casella b, Claudia Pellerito b, Alessandro Longo c, Francesco Ferrante b. 2011. Polyhedron. 30: 1671-1679.
  14. Measurements of the Potentials of Zero Free Charge and Zero Total Charge for 1-thio- ± bβ-D-glucose and DPTL Modified Au(111) Surface in Different Electrolyte Solutions  |  Zhangfei Su, Jay Leitch and Jacek Lipkowski. 2012. Zeitschrift für Physikalische Chemie. 226.
  15. Developing localized surface plasmon resonance biosensor chips and fiber optics via direct surface modification of PMMA optical waveguides  |  Yan Jin, Kok Hou Wong, Anthony M. Granville. 2016. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 492: 100-109.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Thio-β-D-glucose sodium salt, 500 mg

sc-216128A
500 mg
$146.00

1-Thio-β-D-glucose sodium salt, 1 g

sc-216128
1 g
$151.00