Date published: 2026-3-4

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1-(tert-Butoxycarbonyl)-2-pyrrolidinone (CAS 85909-08-6)

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CAS Number:
85909-08-6
Purity:
≥97%
Molecular Weight:
185.22
Molecular Formula:
C9H15NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-(tert-Butoxycarbonyl)-2-pyrrolidinone is used in the field of organic chemistry as a protecting group for amines. Its role in research includes facilitating the synthesis of complex molecules by protecting reactive amine groups during chemical reactions that would otherwise alter their structure. Researchers employ 1-(tert-Butoxycarbonyl)-2-pyrrolidinone because it offers stability under a variety of conditions, yet can be removed under specific, mild circumstances without harming other parts of the molecule. This compound enables the study of reaction mechanisms and the creation of novel compounds, especially in the synthesis of peptides and other nitrogen-containing compounds. Additionally, it serves as an intermediate in the production of more complex chemical entities used in a wide array of research fields.


1-(tert-Butoxycarbonyl)-2-pyrrolidinone (CAS 85909-08-6) References

  1. Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa.  |  Deng, Y., et al. 2017. J Med Chem. 60: 2498-2512. PMID: 28248499
  2. Ruthenium-Pincer-Catalyzed Hydrogenation of Lactams to Amino Alcohols.  |  Chen, J., et al. 2018. Chem Asian J. 13: 2559-2565. PMID: 29888483

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-(tert-Butoxycarbonyl)-2-pyrrolidinone, 25 ml

sc-222637
25 ml
$228.00