Date published: 2025-10-15

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1-Stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine (CAS 59403-53-1)

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CAS Number:
59403-53-1
Molecular Weight:
762.1
Molecular Formula:
C42H84NO8P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine is a phospholipid that functions as a surfactant in experimental applications. It has the ability to reduce surface tension and stabilize emulsions, making it useful in various applications. At the molecular level, this phospholipid interacts with water and lipid molecules, forming a protective layer at the interface. This allows for the dispersion of non-polar substances in aqueous environments, aiding in the solubilization of hydrophobic compounds. Its mechanism of action involves the formation of a lipid bilayer, which can mimic cell membranes and be utilized in studies related to membrane protein interactions.


1-Stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine (CAS 59403-53-1) References

  1. Effect of hydrostatic pressure on the bilayer phase behavior of symmetric and asymmetric phospholipids with the same total chain length.  |  Goto, M., et al. 2008. Biochim Biophys Acta. 1778: 1067-78. PMID: 18190778
  2. Desorption electrospray ionization (DESI) mass spectrometry and tandem mass spectrometry (MS/MS) of phospholipids and sphingolipids: ionization, adduct formation, and fragmentation.  |  Manicke, NE., et al. 2008. J Am Soc Mass Spectrom. 19: 531-43. PMID: 18258448
  3. Pressure study on symmetric and asymmetric phospholipid bilayers: effect of vesicle size on Prodan fluorescence.  |  Goto, M., et al. 2010. Ann N Y Acad Sci. 1189: 68-76. PMID: 20233370
  4. Prodan fluorescence detects the bilayer packing of asymmetric phospholipids.  |  Goto, M., et al. 2011. Colloids Surf B Biointerfaces. 84: 55-62. PMID: 21232926
  5. An (1)O2 route to γ-hydroxyalkenal phospholipids by vitamin E-induced fragmentation of hydroperoxydiene-derived endoperoxides.  |  Gu, X., et al. 2011. Chem Res Toxicol. 24: 1080-93. PMID: 21568309
  6. Nontargeted lipidomic characterization of porcine organs using hydrophilic interaction liquid chromatography and off-line two-dimensional liquid chromatography-electrospray ionization mass spectrometry.  |  Cífková, E., et al. 2013. Lipids. 48: 915-28. PMID: 23912323
  7. Hyper-cell-permeable micelles as a drug delivery carrier for effective cancer therapy.  |  Saw, PE., et al. 2017. Biomaterials. 123: 118-126. PMID: 28167390
  8. Analysis of the Metabolic Characteristics of Serum Samples in Patients With Multiple Myeloma.  |  Du, H., et al. 2018. Front Pharmacol. 9: 884. PMID: 30186161
  9. Distinct metabolic biomarkers to distinguish IgG4-related disease from Sjogren's syndrome and pancreatic cancer and predict disease prognosis.  |  Yan, S., et al. 2022. BMC Med. 20: 497. PMID: 36575511
  10. Bilayer Phase Behavior of an Asymmetric Lipid, 1-stearoyl-2-palmitoylphosphatidylcholine, under High Pressure  |  Goto, M., Kusube, M., Tamai, N., Matsuki, H., & Kaneshina, S. 2007. High Pressure Bioscience and Biotechnology. 1(1): 73-78.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine, 50 mg

sc-220506
50 mg
$138.00