1-Stearoyl-2-Arachidonoyl PC (CAS 35418-59-8)

1-Stearoyl-2-Arachidonoyl PC (phosphatidylcholine) is a phospholipid molecule characterized by a glycerophospholipid backbone where the first position of the glycerol unit is esterified with a stearic acid (saturated fatty acid), and the second position is esterified with arachidonic acid (a polyunsaturated fatty acid). This specific molecular arrangement makes it a critical component in the study of lipid rafts and membrane fluidity within cellular models. Arachidonic acid, known for its role in the biosynthesis of eicosanoids, imparts a particular interest in 1-Stearoyl-2-Arachidonoyl PC for investigating signaling pathways related to inflammation and cellular signaling. In research, this lipid is predominantly utilized to explore the dynamics of cellular membranes, especially the effects of fatty acid composition on membrane properties such as fluidity, phase behavior, and lipid domain formation. The presence of both saturated and unsaturated fatty acids allows for nuanced studies of how these lipids affect the structural and functional aspects of cell membranes, including their interactions with proteins and the activation of specific signaling cascades. Furthermore, this phospholipid serves as a model compound in the study of lipid metabolism and its implications in cellular processes, offering insights into the molecular mechanisms that underlie cell functionality and communication.