Date published: 2025-12-15

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1-Phenylethanol (CAS 98-85-1)

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Alternate Names:
(±)-α-Methylbenzyl alcohol; DL-1-Phenethylalcohol; Methylphenyl carbinol
Application:
1-Phenylethanol is an aromatic alcohol
CAS Number:
98-85-1
Purity:
≥96%
Molecular Weight:
122.16
Molecular Formula:
C8H10O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Phenylethanol (1-PE) is a naturally occurring aromatic alcohol. The significance of 1-Phenylethanol extends to its utility as a model compound in studying the effects of aromatic alcohols on biological systems. It has been extensively employed to investigate the impact of alcohols on protein and nucleic acid metabolism, as well as enzyme function. Moreover, researchers have employed 1-Phenylethanol to examine how aromatic alcohols influence the structure of proteins and DNA. While the precise mechanism of action of 1-Phenylethanol remains a subject of ongoing research, it is believed to operate through the inhibition of enzymes involved in protein and nucleic acid metabolism. Additionally, it is thought to interact with cellular membranes and other components.


1-Phenylethanol (CAS 98-85-1) References

  1. (S)-1-phenylethanol dehydrogenase of Azoarcus sp. strain EbN1, an enzyme of anaerobic ethylbenzene catabolism.  |  Kniemeyer, O. and Heider, J. 2001. Arch Microbiol. 176: 129-35. PMID: 11479712
  2. In vivo micronucleus test in mice with 1-phenylethanol.  |  Engelhardt, G. 2006. Arch Toxicol. 80: 868-72. PMID: 16944102
  3. Photoreduction of 2-methyl-1-nitro-9,10-anthraquinone in the presence of 1-phenylethanol.  |  Gruen, H. and Görner, H. 2008. Photochem Photobiol Sci. 7: 1344-52. PMID: 18958321
  4. Vibrational Raman optical activity of 1-phenylethanol and 1-phenylethylamine: revisiting old friends.  |  Kapitán, J., et al. 2009. Chirality. 21 Suppl 1: E4-12. PMID: 19544353
  5. Optimization of the Production of 1-Phenylethanol Using Enzymes from Flowers of Tea (Camellia sinensis) Plants.  |  Dong, F., et al. 2017. Molecules. 22: PMID: 28098803
  6. Enantioselective complexation of 1-phenylethanol with chiral compounds bearing urea moiety.  |  Cuřínová, P., et al. 2018. Chirality. 30: 798-806. PMID: 29578615
  7. Characterization of enzymes specifically producing chiral flavor compounds (R)- and (S)-1-phenylethanol from tea (Camellia sinensis) flowers.  |  Zhou, Y., et al. 2019. Food Chem. 280: 27-33. PMID: 30642496
  8. Supported Gold Nanoparticles as Catalysts in Peroxidative and Aerobic Oxidation of 1-Phenylethanol under Mild Conditions.  |  Pakrieva, E., et al. 2020. Nanomaterials (Basel). 10: PMID: 31952186
  9. Iron-Catalyzed Oxidation of 1-Phenylethanol and Glycerol With Hydrogen Peroxide in Water Medium: Effect of the Nitrogen Ligand on Catalytic Activity and Selectivity.  |  Ros, D., et al. 2020. Front Chem. 8: 810. PMID: 33195031
  10. The production of enantiomerically pure 1-phenylethanol by enzymatic kinetic resolution method using response surface methodology.  |  Bozan, A., et al. 2020. Turk J Chem. 44: 1352-1365. PMID: 33488235
  11. Dehydrogenation of 1-Phenylethanol Catalyzed by Nickel(II)diphosphine Complexes.  |  Geetha, R., et al. 2021. Acta Chim Slov. 68: 955-960. PMID: 34918757
  12. Deracemization of 1-phenylethanols in a one-pot process combining Mn-driven oxidation with enzymatic reduction utilizing a compartmentalization technique.  |  Sato, H., et al. 2022. RSC Adv. 12: 10619-10624. PMID: 35425022
  13. Accurate Geometry and Non-Covalent Interactions in 1-Phenylethanol and its Monohydrate: A Rotational Study.  |  Zheng, Y., et al. 2023. Chemphyschem. 24: e202200804. PMID: 36537871

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Phenylethanol, 10 g

sc-237618B
10 g
$12.00

1-Phenylethanol, 25 g

sc-237618
25 g
$30.00

1-Phenylethanol, 500 g

sc-237618A
500 g
$66.00