Date published: 2026-2-8

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1-(Perfluorohexyl)octane (CAS 133331-77-8)

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Alternate Names:
1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluorotetradecane
CAS Number:
133331-77-8
Purity:
≥97%
Molecular Weight:
432.26
Molecular Formula:
C14H17F13
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-(Perfluorohexyl)octane, also known as PFHxO, is an artificial organic compound that is part of the perfluoroalkyl group of compounds. Utilized in a multitude of applications, 1-(Perfluorohexyl)octane is a colorless, scentless, non-flammable liquid. It has limited solubility in water but is compatible with the majority of organic solvents. Numerous scientific research applications utilize 1-(Perfluorohexyl)octane, including its use as a solvent, surfactant, and lubricant. Additionally, it serves as a reagent in organic synthesis. 1-(Perfluorohexyl)octane is used to produce various compounds like perfluoroalkyl amines and perfluoroalkyl sulfonamides, and it′s involved in the creation of fluorinated polymers, such as polytetrafluoroethylene (PTFE). As a surfactant, 1-(Perfluorohexyl)octane contributes to reducing a liquid′s surface tension and enhances the solubility of other compounds. When used as a lubricant, it forms a low-friction film on surfaces. Lastly, 1-(Perfluorohexyl)octane is used as a solvent for organic compounds, given its wide miscibility with other organic solvents.


1-(Perfluorohexyl)octane (CAS 133331-77-8) References

  1. Screening of semifluorinated n-alkanes by gas chromatography coupled to dielectric barrier discharge ionization mass spectrometry.  |  Hagenhoff, S., et al. 2018. Rapid Commun Mass Spectrom. 32: 1092-1098. PMID: 29660193
  2. Analyte-Tailored Controlled Atmosphere Improves Dielectric Barrier Discharge Ionization Mass Spectrometry Performance.  |  Vogel, P., et al. 2019. Anal Chem. 91: 3733-3739. PMID: 30672695
  3. Systematic developmental toxicity assessment of a structurally diverse library of PFAS in zebrafish.  |  Truong, L., et al. 2022. J Hazard Mater. 431: 128615. PMID: 35263707
  4. Ionization of semi-fluorinated n-alkanes in controlled atmosphere using flexible micro-tube plasma (FμTP) ionization source with square- and sine-wave voltage.  |  Tian, C., et al. 2022. Talanta. 249: 123662. PMID: 35691129
  5. Targeted Per- and Polyfluoroalkyl substances (PFAS) assessments for high throughput screening: Analytical and testing considerations to inform a PFAS stock quality evaluation framework.  |  Smeltz, MG., et al. 2023. Toxicol Appl Pharmacol. 459: 116355. PMID: 36535553

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-(Perfluorohexyl)octane, 1 g

sc-255759
1 g
$260.00

1-(Perfluorohexyl)octane, 5 g

sc-255759A
5 g
$666.00