1-Palmitoyl-sn-glycero-3-phospho-sn-1-glycerol sodium salt (CAS 30227-18-0)

1-Palmitoyl-sn-glycero-3-phospho-sn-1-glycerol sodium salt is a synthetic phospholipid extensively used in the study of membrane biophysics and lipid biochemistry. This compound, featuring a palmitoyl fatty acid attached to a glycerol backbone with an additional phosphoglycerol group, is crucial for investigating the structural dynamics of lipid bilayers and their biological functions. The inclusion of the sodium salt enhances its solubility and facilitates its integration into aqueous solutions, making it ideal for creating model membranes and liposomes. Research utilizing this phospholipid focuses on understanding how specific lipid compositions influence membrane fluidity, permeability, and the interaction with proteins and peptides. These studies are vital for elucidating mechanisms of vesicle formation, membrane fusion, and the role of lipids in signaling pathways. Moreover, the phosphoglycerol headgroup in this molecule allows researchers to explore the effects of headgroup charge on membrane properties, including interactions with ions and other charged molecules within the cellular environment. These investigations contribute significantly to the fundamental understanding of membrane-associated processes, providing insights into cellular functionality and lipidomics.