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1-Palmitoyl-rac-glycero-3-phosphocholine (CAS 17364-18-0)

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Alternate Names:
1-Hexadecanoyl-rac-glycero-3-phosphocholine
CAS Number:
17364-18-0
Molecular Weight:
495.6
Molecular Formula:
C24H50NO7P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Palmitoyl-rac-glycero-3-phosphocholine, commonly known as palmitoyl phosphatidylcholine (PPC), has emerged as a significant compound in lipid research due to its crucial role in cell membrane structure and function. PPC is a major constituent of cell membranes, particularly in mammalian cells, where it contributes to membrane fluidity and stability. Research has explaind its involvement in various cellular processes, including membrane trafficking, cellular signaling, and lipid metabolism. PPC is also recognized for its interactions with membrane proteins and its ability to modulate their activity and localization. Furthermore, PPC has been utilized as a model lipid in membrane biophysics and lipidomics studies, providing insights into lipid-lipid and lipid-protein interactions within biological membranes. Moreover, PPC-containing liposomes have been employed as delivery systems for various bioactive compounds, including drugs and nucleic acids, in biomedical research. Investigations into the biophysical properties and functional roles of PPC in cellular membranes continue to contribute to our understanding of membrane biology.


1-Palmitoyl-rac-glycero-3-phosphocholine (CAS 17364-18-0) References

  1. Impact of Extracellular Fatty Acids and Oxygen Tension on Lipid Synthesis and Assembly in Pancreatic Cancer Cells.  |  Downes, DP., et al. 2020. ACS Chem Biol. 15: 1892-1900. PMID: 32396332
  2. Effects of specific fatty acid acylation of phospholipase A2 on its interfacial binding and catalysis.  |  Shen, Z., et al. 1994. Biochemistry. 33: 11598-607. PMID: 7918373
  3. Roles of surface hydrophobic residues in the interfacial catalysis of bovine pancreatic phospholipase A2.  |  Lee, BI., et al. 1996. Biochemistry. 35: 4231-40. PMID: 8672459
  4. Lipid structure and not membrane structure is the major determinant in the regulation of protein kinase C by phosphatidylserine.  |  Johnson, JE., et al. 1998. Biochemistry. 37: 12020-5. PMID: 9724512
  5. Membrane penetration of cytosolic phospholipase A2 is necessary for its interfacial catalysis and arachidonate specificity.  |  Lichtenbergova, L., et al. 1998. Biochemistry. 37: 14128-36. PMID: 9760249
  6. Surface chemical properties of homologs and analogs of lysophosphatidylcholine and lysophosphatidylethanolamine in water  |  Teruko Yamanaka a, Norihiko Ogihara a, Takahiro Ohhori a, Hideko Hayashi a, Toshio Muramatsu b. 1997. Chemistry and Physics of Lipids. 90: 97-107.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Palmitoyl-rac-glycero-3-phosphocholine, 50 mg

sc-208684
50 mg
$209.00

1-Palmitoyl-rac-glycero-3-phosphocholine, 250 mg

sc-208684A
250 mg
$719.00