1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-sn-1-glycerol sodium salt (CAS 268550-95-4)

1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-sn-1-glycerol sodium salt is a synthetic phospholipid frequently used in the study of cellular membranes and lipid-based assemblies in biophysical research. This compound is particularly characterized by having palmitic acid at the sn-1 position and oleic acid at the sn-2 position of the glycerol backbone, with a phosphoglycerol group linked to another glycerol molecule. The structure facilitates the exploration of lipid bilayer properties, such as fluidity, phase transition, and permeability, under various conditions. It also provides insights into the effects of unsaturation and chain length on the behavior of lipid membranes. The sodium salt form increases its solubility, making it easier to handle in experimental studies involving liposome and vesicle formation, crucial for investigating transport mechanisms across the lipid bilayers and the interaction of membranes with proteins and other bioactive molecules. Research with this specific phospholipid aids in understanding the fundamental biophysical aspects of how lipid composition and structure influence membrane function, particularly in the areas of vesicular trafficking and membrane fusion.