(+)-(1-Oxyl-2,2,5,5-tetramethylpyrrolidin-3-yl)methyl Methanethiosulfonate CAS: 681034-14-0
MF: C10H20NO3S2
MW: 266.40
A nitroxide thiol-specific spin label.

(+)-(1-Oxyl-2,2,5,5-tetramethylpyrrolidin-3-yl)methyl Methanethiosulfonate (CAS 681034-14-0)

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Application: (+)-(1-Oxyl-2,2,5,5-tetramethylpyrrolidin-3-yl)methyl Methanethiosulfonate is a nitroxide thiol-specific spin label
CAS Number: 681034-14-0
Molecular Weight: 266.40
Molecular Formula: C10H20NO3S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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A paramagnetic nitroxide thiol-specific spin label that is highly reactive. Used in studies to monitor intermolecular interactions amongst various tau molecules. Also used in experiments with cysteine to add a nitroxide side chain that exhibits greater mobility contrast between helix surfaces and tertiary contact sites.


References

1. Mchaourab, H.S., et al. 1999. Biochemistry. 38: 2947-2955. PMID: 10074347
2. Peterson, D.W., et al. 2008. Biochemistry. 47: 7393-7404. PMID: 18558718
3. Berliner, L.J., et al. 1982. Anal. Biochem. 119: 450-455. PMID: 6280514
4. Dmitriev, O.Y., et al. 2008. Biochim. Biophys. Acta. 1777: 227-237. PMID: 18178144

Physical State :
Solid
Solubility :
Soluble in DMSO and Ethanol
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
29986225
SMILES :
ON1C(C)(C)C[[email protected]@H](CSS(=O)(=O)C)C1(C)C

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Certificate of Analysis

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