Date published: 2025-10-1

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1-oxazolo[4,5-b]pyridin-2-yl-9-octadecyn-1-one (CAS 288862-89-5)

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Application:
1-oxazolo[4,5-b]pyridin-2-yl-9-octadecyn-1-one is a potent inhibitor of fatty acid amide hydrolase
CAS Number:
288862-89-5
Purity:
>98%
Molecular Weight:
382.5
Molecular Formula:
C24H34N2O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-oxazolo[4,5-b]pyridin-2-yl-9-octadecyn-1-one is a selective, potent inhibitor of rat FAAH exhibiting a Ki value of 0.14 nM. Fatty acid amide hydrolase (FAAH) is the enzyme responsible for inactivation and hydrolysis of fatty acid amides including anandamide and oleamide. 1-oxazolo[4,5-b]pyridin-2-yl-9-octadecyn-1-one is approximately 580 fold more potent than oleyl trifluoromethyl ketone when assayed under the same conditions.


1-oxazolo[4,5-b]pyridin-2-yl-9-octadecyn-1-one (CAS 288862-89-5) References

1 Boger, D.L., Sato, H., Lerner, A.E., et al. Exceptionally potent inhibitors of fatty acid amide hydrolase: The enzyme responsible for degradation of endogenous oleamide and anandamide. Proc Natl Acad Sci USA 97 5044-5049 (2000).

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-oxazolo[4,5-b]pyridin-2-yl-9-octadecyn-1-one, 100 µg

sc-204951
100 µg
$56.00

1-oxazolo[4,5-b]pyridin-2-yl-9-octadecyn-1-one, 500 µg

sc-204951A
500 µg
$252.00