Molecular structure of 1-O-Hexadecyl-sn-glycerol, CAS Number: 506-03-6
1-O-Hexadecyl-sn-glycerol (CAS 506-03-6)
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Application:
1-O-Hexadecyl-sn-glycerol is a naturally occuring ether lipid
CAS Number:
506-03-6
Purity:
≥98%
Molecular Weight:
316.52
Molecular Formula:
C19H40O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
1-O-Hexadecyl-sn-glycerol is a naturally occuring ether lipid. Reduces myocardial ischemia/reperfusion injury. 1-O-Hexadecyl-sn-glycerol can be used to improve cellular uptake and to reduce toxicity of phosphorothioated antisense oligodeoxyribonucleotides when conjugated at the 3′-end. Inhibits cellular proliferation, anchorage-independent growth and cellular invasion in human prostate cancer cell lines.
1-O-Hexadecyl-sn-glycerol (CAS 506-03-6) References
- 3'-End conjugates of minimally phosphorothioate-protected oligonucleotides with 1-O-hexadecylglycerol: synthesis and anti-ras activity in radiation-resistant cells. | Rait, A., et al. 2000. Bioconjug Chem. 11: 153-60. PMID: 10725091
- Inhibitory effect of 1-O (2 methoxy) hexadecyl glycerol and phenylbutyrate on the malignant properties of human prostate cancer cells. | Reynolds, S., et al. 2000. Clin Exp Metastasis. 18: 309-12. PMID: 11448061
- Natural 1-O-alkylglycerols reduce platelet-activating factor-induced release of [3H]-serotonin in rabbit platelets. | Pédrono, F., et al. 2004. Prostaglandins Leukot Essent Fatty Acids. 71: 19-23. PMID: 15172680
- Synthesis and biological properties of the fluorescent ether lipid precursor 1-O-[9'-(1''-pyrenyl)]nonyl-sn-glycerol. | Zheng, H., et al. 2006. J Lipid Res. 47: 633-42. PMID: 16369049
- Biosynthesis of alkyl lysophosphatidic acid by diacylglycerol kinases. | Gellett, AM., et al. 2012. Biochem Biophys Res Commun. 422: 758-63. PMID: 22627129
- Tetrahydrobiopterin and alkylglycerol monooxygenase substantially alter the murine macrophage lipidome. | Watschinger, K., et al. 2015. Proc Natl Acad Sci U S A. 112: 2431-6. PMID: 25675482
- Correlation of ether lipid content of human leukemia cell lines and their susceptibility to 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine. | Chabot, MC., et al. 1989. Cancer Res. 49: 4441-5. PMID: 2743333
- 1-O-alkylglycerols from the hepatopancreas of the crab Paralithodes camtschaticus, liver of the squid Berryteuthis magister, and liver of the skate Bathyraja parmifera, and their anticancer activity on human melanoma cells. | Latyshev, NA., et al. 2019. J Food Biochem. 43: e12828. PMID: 31353521
- A possible role for plasmalogens in protecting animal cells against photosensitized killing. | Zoeller, RA., et al. 1988. J Biol Chem. 263: 11590-6. PMID: 3403547
- The degradation of platelet-activating factor and related lipids: susceptibility to phospholipases C and D. | Wilcox, RW., et al. 1987. Lipids. 22: 800-7. PMID: 3444369
- Cytotoxicity of ester and ether lysophospholipids on Leishmania donovani promastigotes. | Achterberg, V. and Gercken, G. 1987. Mol Biochem Parasitol. 23: 117-22. PMID: 3574353
- Myocardial salvage by 1-O-hexadecyl-Sn-glycerol: possible role of peroxisomal dysfunction in ischemia reperfusion injury. | Maulik, N., et al. 1994. J Cardiovasc Pharmacol. 24: 486-92. PMID: 7799644
- Myocardial salvage by chimyl alcohol: possible role of peroxisomal dysfunction in reperfusion injury. | Maulik, N., et al. 1994. Ann N Y Acad Sci. 723: 380-4. PMID: 8030890
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-O-Hexadecyl-sn-glycerol, 1 g | sc-202394 | 1 g | $327.00 | |||
1-O-Hexadecyl-sn-glycerol, 5 g | sc-202394A | 5 g | $1215.00 |