Date published: 2025-11-14

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1-O-Hexadecyl-rac-glycerol (CAS 6145-69-3)

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Alternate Names:
DL-alpha-hexadecylglycerol; Chimyl alcohol; 1-O-Palmityl-rac-glycerol
Application:
1-O-Hexadecyl-rac-glycerol is a crystalline alcohol
CAS Number:
6145-69-3
Purity:
≥98%
Molecular Weight:
316.52
Molecular Formula:
C19H40O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-O-Hexadecyl-rac-glycerol, also known as hexadecylglycerol or batyl alcohol, is a chemical compound that belongs to the family of glycerol ethers. It is characterized by the presence of a hexadecyl (16-carbon) alkyl chain attached to the first carbon atom of the glycerol backbone. Hexadecylglycerol has been studied for its potential immunomodulatory effects. It has been investigated for its ability to modulate immune responses and regulate the production of cytokines and other immune mediators.


1-O-Hexadecyl-rac-glycerol (CAS 6145-69-3) References

  1. 3'-End conjugates of minimally phosphorothioate-protected oligonucleotides with 1-O-hexadecylglycerol: synthesis and anti-ras activity in radiation-resistant cells.  |  Rait, A., et al. 2000. Bioconjug Chem. 11: 153-60. PMID: 10725091
  2. GPI-alkaline phosphatase insertion into phosphatidylcholine monolayers: phase behavior and morphology changes.  |  Kouzayha, A. and Besson, F. 2005. Biochem Biophys Res Commun. 333: 1315-21. PMID: 15979580
  3. Two-dimensional facets in Langmuir monolayers of 1-O-hexadecyl-rac-glycerol at the air-water interface.  |  Islam, MN. and Kato, T. 2006. J Colloid Interface Sci. 296: 263-8. PMID: 16182305
  4. The acylation of lipophilic alcohols by lysosomal phospholipase A2.  |  Abe, A., et al. 2007. J Lipid Res. 48: 2255-63. PMID: 17626977
  5. Alkyl-glycerol rescues plasmalogen levels and pathology of ether-phospholipid deficient mice.  |  Brites, P., et al. 2011. PLoS One. 6: e28539. PMID: 22163031
  6. Dependence of an alkyl glycol-ether monooxygenase activity upon tetrahydropterins.  |  Kaufman, S., et al. 1990. Biochim Biophys Acta. 1040: 19-27. PMID: 2378898
  7. Critical role of the peroxisomal protein PEX16 in white adipocyte development and lipid homeostasis.  |  Hofer, DC., et al. 2017. Biochim Biophys Acta Mol Cell Biol Lipids. 1862: 358-368. PMID: 28017862
  8. Mesoscopic characterization of amphiphilic monoglycerol monolayers.  |  Vollhardt, D. 2018. Adv Colloid Interface Sci. 258: 36-46. PMID: 30056937
  9. Lattice structures and phase behavior of amphiphilic monoglycerol monolayers.  |  Vollhardt, D. and Brezesinski, G. 2019. Adv Colloid Interface Sci. 273: 102030. PMID: 31494338
  10. Release of 1-O-alkylglyceryl 3-phosphorylcholine, O-deacetyl platelet-activating factor, from leukocytes: chemical ionization mass spectrometry of phospholipids.  |  Polonsky, J., et al. 1980. Proc Natl Acad Sci U S A. 77: 7019-23. PMID: 6938950
  11. Lipase-catalyzed monoesterification of 1-O-hexadecylglycerol in organic solvents.  |  Bertello, LE., et al. 1997. Lipids. 32: 907-11. PMID: 9270985
  12. The phase behavior of an ether lipid monolayer compared with an ester lipid monolayer  |  , et al. 01 January 2007. Trends in Colloid and Interface Science VIII. volume 97): pp 302–306Cite as.
  13. Chiral Discrimination Effects in Langmuir Monolayers of 1-O-Hexadecyl Glycerol  |  N. Nandi, D. Vollhardt, and G. Brezesinski. Publication Date:December 9, 2003. J. Phys. Chem. B 2004,,. 108, 1: 327–335.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-O-Hexadecyl-rac-glycerol, 1 g

sc-205917
1 g
$140.00