Molecular structure of 1-O-Hexadecyl-2-O-methyl-rac-glycerol, CAS Number: 111188-59-1
1-O-Hexadecyl-2-O-methyl-rac-glycerol (CAS 111188-59-1)
Application:
1-O-Hexadecyl-2-O-methyl-rac-glycerol is an inhibitor of protein kinase C
CAS Number:
111188-59-1
Purity:
≥97%
Molecular Weight:
330.55
Molecular Formula:
C20H42O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
1-O-Hexadecyl-2-O-methyl-rac-glycerol is an inhibitor of protein kinase C (PKC).
1-O-Hexadecyl-2-O-methyl-rac-glycerol (CAS 111188-59-1) References
- Phosphatidylinositol transfer proteins and protein kinase C make separate but non-interacting contributions to the phosphorylation state necessary for secretory competence in rat mast cells. | Pinxteren, JA., et al. 2001. Biochem J. 356: 287-96. PMID: 11336662
- Evidence for the functional involvement of protein kinase C in the action of 1,25-dihydroxyvitamin D3 in bone. | van Leeuwen, JP., et al. 1992. J Biol Chem. 267: 12562-9. PMID: 1320001
- Possible existence of two subsets of platelet-activating factor receptor to mediate polyphosphoinositide breakdown and calcium influx in neuroblastoma x glioma hybrid NG 108-15 cells. | Chau, LY., et al. 1992. J Neurochem. 59: 1090-8. PMID: 1322966
- Characterization of p21Ras-mediated apoptosis induced by protein kinase C inhibition and application to human tumor cell lines. | Liou, JS., et al. 2004. J Cell Physiol. 198: 277-94. PMID: 14603530
- 1-O-hexadecyl-2-Q-methylglycerol, a novel inhibitor of protein kinase C, inhibits the respiratory burst in human neutrophils. | Kramer, IM., et al. 1989. J Biol Chem. 264: 5876-84. PMID: 2925639
- Evidence that the activation of an inactive pool of membrane-associated protein kinase C is linked to the IL-2-dependent survival of T lymphocytes. | Lu, Y., et al. 1994. J Immunol. 153: 1495-504. PMID: 8046229
- Diacylglycerol and alkylacylglycerol stimulate ram sperm phospholipase A2. | Roldan, ER., et al. 1994. Int J Biochem. 26: 951-8. PMID: 8063019
- Mastoparan stimulates exocytosis at a Ca(2+)-independent late site in stimulus-secretion coupling. Studies with the RINm5F beta-cell line. | Komatsu, M., et al. 1993. J Biol Chem. 268: 23297-306. PMID: 8226853
- Plasmin is a potent and specific chemoattractant for human peripheral monocytes acting via a cyclic guanosine monophosphate-dependent pathway. | Syrovets, T., et al. 1997. Blood. 89: 4574-83. PMID: 9192782
- Sensitization of human umbilical vein endothelial cells to Shiga toxin: involvement of protein kinase C and NF-kappaB. | Louise, CB., et al. 1997. Infect Immun. 65: 3337-44. PMID: 9234795
- Lipoprotein(a) is a potent chemoattractant for human peripheral monocytes. | Syrovets, T., et al. 1997. Blood. 90: 2027-36. PMID: 9292539
Inhibitor of:
PKC, and Ser/Thr Protein Kinase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-O-Hexadecyl-2-O-methyl-rac-glycerol, 250 mg | sc-201998 | 250 mg | $196.00 | |||
1-O-Hexadecyl-2-O-methyl-rac-glycerol, 1 g | sc-201998A | 1 g | $592.00 |