1-O-Dimethoxytrityl-2-(N-Fmoc)-4-aminobutyl)-1,3-propanediol (CAS 147190-32-7)

1-O-Dimethoxytrityl-2-(N-Fmoc)-4-aminobutyl)-1,3-propanediol is a compound used primarily in the field of peptide synthesis research. It acts as a protecting group for amino acids during the synthesis process, ensuring that the amino and hydroxyl functional groups do not react prematurely. The dimethoxytrityl (DMT) part of the molecule is used to protect the hydroxyl group, while the 9-fluorenylmethyloxycarbonyl (Fmoc) group protects the amine. This dual protection is particularly valuable in the synthesis of complex peptides and in solid-phase peptide synthesis techniques where stepwise elongation of the peptide chain is required. The compound provides stability for the growing peptide chain and can be selectively removed at different stages, which is for the correct folding and function of the synthesized peptides. Researchers in organic chemistry use this compound to explore new methodologies for peptide construction, aiming to improve efficiency and yield in peptide synthesis.