1-O-Acetyl-2,3,5-tri-O-benzyl-D-ribofuranose (CAS 58381-23-0)

1-O-Acetyl-2,3,5-tri-O-benzyl-D-ribofuranose is a chemically modified ribose derivative that is extensively used in the field of nucleoside synthesis and carbohydrate chemistry. This compound features acetyl and benzyl protective groups which safeguard the furanose ring′s reactive hydroxyl groups during complex synthetic operations, thereby allowing for selective chemical modifications at strategic positions on the sugar molecule. Its utility is particularly evident in the synthesis of modified nucleosides and nucleotides, where precision and control over glycosidic bond formation are paramount. In research, this sugar derivative serves as a key intermediate for constructing molecules that mimic the structure of naturally occurring nucleosides, which are fundamental components of RNA and DNA. These studies are critical for advancing our understanding of the molecular structures that underlie genetic material and for developing new methods in synthetic biology. Moreover, the protective groups in 1-O-Acetyl-2,3,5-tri-O-benzyl-D-ribofuranose facilitate the exploration of new synthetic pathways that can lead to the discovery of novel nucleoside analogues with potential applications in materials science and nanotechnology, rather than pharmaceuticals. This research contributes significantly to the broader fields of organic chemistry and molecular biology, providing insights into the synthesis and function of complex biomolecules.