1-O-Acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose-13C5 (CAS 6974-32-9 (unlabeled))

1-O-Acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose-13C5 is a stable isotopically labeled derivative of ribose, crucial for elucidating metabolic pathways and investigating nucleic acid structure and function. Its incorporation of 13C isotopes enables precise tracking of metabolic fluxes and elucidation of nucleotide biosynthesis pathways via nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS) techniques. This labeled compound serves as a valuable tool in stable isotope-resolved metabolomics (SIRM) studies, allowing researchers to trace the fate of carbon atoms in cellular metabolism and identify metabolic alterations associated with diseases or physiological states. Moreover, 1-O-Acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose-13C5 finds applications in nucleic acid labeling experiments, where it serves as a substrate for enzymatic reactions, such as RNA transcription or oligonucleotide synthesis, enabling the generation of isotopically labeled RNA or DNA molecules for functional and structural studies. Additionally, this isotopically labeled ribose derivative is utilized in isotope-edited NMR experiments for probing nucleic acid-protein interactions and elucidating RNA or DNA folding dynamics, contributing to advancements in the field of structural biology and molecular biophysics. Overall, its versatility and utility make it an indispensable tool in various research applications related to nucleic acids and cellular metabolism.