1-Naphthylacetyl Spermine (CAS 122306-11-0)
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1-Naphthylacetyl Spermine, a polyamine amide, emerges as a critical tool in neuroscience research for its potent inhibition of Spermidine uptake, reflecting its nuanced role in cellular mechanisms related to polyamine metabolism. Its ability to act as a selective antagonist of GluR, specifically targeting Ca2+-permeable AMPA receptors, positions it as a valuable asset in the study of glutamate-mediated excitotoxicity. This selective antagonism is particularly significant given the AMPA receptor′s composition of various subunits (GluR-1, 2, 3, 4), which are integral to synaptic transmission and plasticity. By safeguarding hippocampal neurons from the detrimental effects of global ischemia-induced cell death, 1-Naphthylacetyl Spermine offers a unique vantage point for dissecting the pathways of neuronal injury and survival, further underscoring its utility in advancing our understanding of neuroprotective strategies within the realm of neurological research.
1-Naphthylacetyl Spermine (CAS 122306-11-0) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-Naphthylacetyl Spermine, 25 mg | sc-206189 | 25 mg | $382.00 |