Date published: 2025-10-15

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1-Naphthyl-β-D-glucuronide sodium salt (CAS 83833-12-9)

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Alternate Names:
1-Naphthyl-β-D-glucuronic acid sodium salt
Application:
1-Naphthyl-β-D-glucuronide sodium salt is a chromogenic substrate
CAS Number:
83833-12-9
Purity:
≥97%
Molecular Weight:
342.28
Molecular Formula:
C16H15O7•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Naphthyl β-D-glucuronide sodium salt is a compound often used in enzymology and analytical biochemistry. It serves as a chromogenic substrate for the enzyme β-glucuronidase, which upon cleavage releases a naphthol moiety that can be easily detected. This property is harnessed in assays to measure the activity of β-glucuronidase, an enzyme important in the metabolism of glucuronides. The compound is also utilized in environmental studies to monitor microbial degradation processes, as the presence of β-glucuronidase activity can indicate the metabolic potential of the microbial community. Additionally, 1-Naphthyl β-D-glucuronide sodium salt is used in the synthesis of labeled compounds where the naphthyl group serves as a detectable moiety, aiding in the traceability and analysis of the target molecules in complex systems.


1-Naphthyl-β-D-glucuronide sodium salt (CAS 83833-12-9) References

  1. Simultaneous measurement of urinary bisphenol A and alkylphenols by automated solid-phase extractive derivatization gas chromatography/mass spectrometry.  |  Kuklenyik, Z., et al. 2003. Anal Chem. 75: 6820-5. PMID: 14670041
  2. Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier.  |  Ohtsuki, S., et al. 2004. J Pharmacol Exp Ther. 309: 1273-81. PMID: 14762099
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  4. Characterization and profiling of hepatic cytochromes P450 and phase II xenobiotic-metabolizing enzymes in beluga whales (Delphinapterus leucas) from the St. Lawrence River Estuary and the Canadian Arctic.  |  McKinney, MA., et al. 2004. Aquat Toxicol. 69: 35-49. PMID: 15210296
  5. The determination of occupational exposure to polycyclic aromatic hydrocarbons by the analysis of 1-hydroxypyrene in urine using a simple automated online column switching device and high-performance liquid chromatography.  |  Hu, J., et al. 2012. J Anal Toxicol. 36: 334-9. PMID: 22582268
  6. Quantitative determination of hydroxy polycylic aromatic hydrocarbons as a biomarker of exposure to carcinogenic polycyclic aromatic hydrocarbons.  |  Woudneh, MB., et al. 2016. J Chromatogr A. 1454: 93-100. PMID: 27266337

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Naphthyl-β-D-glucuronide sodium salt, 50 mg

sc-282181
50 mg
$194.00

1-Naphthyl-β-D-glucuronide sodium salt, 100 mg

sc-282181A
100 mg
$357.00