Molecular structure of 1-Methylchrysene, CAS Number: 3351-28-8
1-Methylchrysene (CAS 3351-28-8)
Application:
1-Methylchrysene is an aryl hydrocarbon receptor (AhR) agonist
CAS Number:
3351-28-8
Molecular Weight:
242.31
Molecular Formula:
C19H14
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
1-Methylchrysene (1-MC), a polycyclic aromatic hydrocarbon (PAH), is a prevalent constituent of combustion byproducts. This compound is recognized as a carcinogen, associated with various adverse health outcomes. 1-Methylchrysene finds extensive application in laboratory experiments. Moreover, it serves as an essential model compound to unravel the intricate mechanisms underlying carcinogenesis. The metabolism of 1-Methylchrysene involves the activity of cytochrome P450 enzymes, catalyzing the formation of reactive metabolites that can bind to DNA and induce mutations.
1-Methylchrysene (CAS 3351-28-8) References
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- Methylated polycyclic aromatic hydrocarbons and/or their metabolites are important contributors to the overall estrogenic activity of polycyclic aromatic hydrocarbon-contaminated soils. | Lam, MM., et al. 2018. Environ Toxicol Chem. 37: 385-397. PMID: 28834568
- Methylated PACs are more potent than their parent compounds: A study of aryl hydrocarbon receptor-mediated activity, degradability, and mixture interactions in the H4IIE-luc assay. | Lam, MM., et al. 2018. Environ Toxicol Chem. 37: 1409-1419. PMID: 29334126
- Aryl hydrocarbon receptor signaling, toxicity, and gene expression responses to mono-methylchrysenes. | Alqassim, AY., et al. 2019. Environ Toxicol. 34: 992-1000. PMID: 31087746
- Regiospecific Photochemical Synthesis of Methylchrysenes. | Böhme, T., et al. 2022. Molecules. 28: PMID: 36615430
- Chrysene and methylchrysenes: presence in tobacco smoke and carcinogenicity. | Hecht, SS., et al. 1974. J Natl Cancer Inst. 53: 1121-33. PMID: 4427391
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-Methylchrysene, 10 mg | sc-229797 | 10 mg | $168.00 |