Date published: 2025-9-5

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1-Methyl-4-imidazoleacetic acid hydrochloride (CAS 35454-39-8)

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Application:
CAS Number:
35454-39-8
Molecular Weight:
176.60
Molecular Formula:
C6H8N2O2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Methyl-4-imidazoleacetic acid hydrochloride is a structural analog of imidazoleacetic acid, which is known for its biological activity, particularly in relation to histamine pathways and responses. It′s recognized for its modulation of receptors and enzymatic activities related to the histamine metabolic pathway. Despite its structural relation to histamine, 1-Methyl-4-imidazoleacetic acid hydrochloride does not share histamine′s ability to modulate the binding of histamine-coupled erythrocytes to alveolar macrophages. It can be utilized as an intermediate in the synthesis of various chemical products.


1-Methyl-4-imidazoleacetic acid hydrochloride (CAS 35454-39-8) References

  1. Surrogate matrix and surrogate analyte approaches for definitive quantitation of endogenous biomolecules.  |  Jones, BR., et al. 2012. Bioanalysis. 4: 2343-56. PMID: 23088461
  2. Urinary metabolomic profiling for noninvasive diagnosis of acute T cell-mediated rejection after kidney transplantation.  |  Kim, SY., et al. 2019. J Chromatogr B Analyt Technol Biomed Life Sci. 1118-1119: 157-163. PMID: 31054449
  3. Histamine and metabolites: their effects and interactions with convulsants on brain stem neurones.  |  Haas, HL., et al. 1973. Brain Res. 51: 269-78. PMID: 4145193
  4. Enhancement of human eosinophil complement receptors by pharmacologic mediators.  |  Anwar, AR. and Kay, B. 1978. J Immunol. 121: 1245-50. PMID: 701794

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Methyl-4-imidazoleacetic acid hydrochloride, 10 mg

sc-222712
10 mg
$61.00

1-Methyl-4-imidazoleacetic acid hydrochloride, 250 mg

sc-222712A
250 mg
$612.00