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1-Methoxy-2-propanol (CAS 107-98-2)

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Alternate Names:
Propylene glycol methyl ether; Propyleneglycol monomethyl ether
Application:
1-Methoxy-2-propanol is a glycol ether and a good biological indicator of exposure
CAS Number:
107-98-2
Purity:
≥99%
Molecular Weight:
90.12
Molecular Formula:
C4H10O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Methoxy-2-propanol, also known as propylene glycol methyl ether (PGME), is a chemical compound that belongs to the glycol ether family, a group of organic compounds derived from alkyl ethers of ethylene glycol or propylene glycol. Structurally, it consists of a propylene glycol unit with a methoxy group attached, which enhances its solubility in water and organic solvents. This compound is a colorless liquid with a mild odor and is noted for its excellent solvent properties, particularly for resins, coatings, and inks. In research, 1-Methoxy-2-propanol is frequently used as a solvent due to its ability to dissolve both polar and non-polar substances, which makes it highly versatile for various chemical processes and formulations. Its role in research extends to its use as a carrier solvent in the synthesis of pharmaceuticals, where it aids in improving the solubility and handling of hydrophobic compounds. Additionally, its relatively low toxicity and good environmental profile make it a preferred choice in studies aimed at developing safer and more sustainable solvent systems. The chemical′s low volatility and ability to form azeotropes with water are also beneficial in processes that require precise control of solvent evaporation rates. Beyond its solvent usage, 1-Methoxy-2-propanol is studied for its physicochemical properties, such as its boiling point, viscosity, and miscibility with water, which are important parameters in the design of industrial applications and environmental impact assessments.


1-Methoxy-2-propanol (CAS 107-98-2) References

  1. Evaluation of exposure to 1-alkoxy-2-propanols and 1-(2-methoxy-1-methylethoxy)-2-propanol by the analysis of the parent compounds in urine.  |  Laitinen, J., et al. 2006. Toxicol Lett. 162: 186-94. PMID: 16289654
  2. Biological treatment of a contaminated gaseous emission from a leather industry in a suspended-growth bioreactor.  |  Carvalho, MF., et al. 2009. Chemosphere. 74: 232-8. PMID: 18990430
  3. Sensitive headspace gas chromatography analysis of free and conjugated 1-methoxy-2-propanol in urine.  |  Tomicic, C. and Berode, M. 2010. Anal Bioanal Chem. 396: 2709-14. PMID: 20155252
  4. Anaerobic removal of 1-methoxy-2-propanol under ambient temperature in an EGSB reactor.  |  Lafita, C., et al. 2015. Bioprocess Biosyst Eng. 38: 2137-46. PMID: 26288950
  5. Keto-ether and glycol-ethers in the troposphere: reactivity toward OH radicals and Cl atoms, global lifetimes, and atmospheric implications.  |  Barrera, JA., et al. 2017. Environ Sci Pollut Res Int. 24: 26049-26059. PMID: 28942560
  6. Anaerobic degradation of glycol ether-ethanol mixtures using EGSB and hybrid reactors: Performance comparison and ether cleavage pathway.  |  Ferrero, P., et al. 2018. J Environ Manage. 213: 159-167. PMID: 29494932
  7. Major component causing neurological toxicity in acute glufosinate ammonium poisoning: determination of glufosinate, 1-methoxy-2-propanol, and ammonia in serum and cerebrospinal fluid.  |  Yeon, S., et al. 2022. Clin Toxicol (Phila). 60: 286-292. PMID: 34269144
  8. Insights into the mechanism of the solvolysis of propylene oxide over titanium silicalite-1: a theoretical study.  |  Qin, Q., et al. 2023. Phys Chem Chem Phys. 25: 21358-21375. PMID: 37530074
  9. Determination of 1-methoxy-2-propanol and its metabolite 1,2-propanediol in rat and mouse plasma by gas chromatography.  |  Ferrala, NF., et al. 1994. J Chromatogr B Biomed Appl. 660: 291-6. PMID: 7866519
  10. Biological monitoring of occupational exposure to 1-methoxy-2-propanol.  |  Laitinen, J., et al. 1997. J Chromatogr B Biomed Sci Appl. 694: 93-8. PMID: 9234852

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Methoxy-2-propanol, 1 L

sc-237577
1 L
$61.00

1-Methoxy-2-propanol, 4 L

sc-237577A
4 L
$153.00