Molecular structure of 1-Hydroxypyridine-2-thione zinc salt, CAS Number: 1121-31-9
1-Hydroxypyridine-2-thione zinc salt (CAS 13463-41-7)
Alternate Names:
Mercaptopyridine N-oxide zinc salt; Zinc pyrithione; Bis(2-pyridylthio) Zinc 1,1′-Dioxide; 2-Pyridinethiol 1-Oxide Zinc Salt
Application:
1-Hydroxypyridine-2-thione zinc salt is a useful building block for chemical synthesis
CAS Number:
13463-41-7
Purity:
>97%
Molecular Weight:
317.70
Molecular Formula:
C10H8N2O2S2Zn
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
1-Hydroxypyridine-2-thione zinc salt is a compound that functions as a chelating agent in experimental applications. It acts by forming stable complexes with metal ions, particularly with zinc. This interaction at the molecular level allows for the removal of metal ions from solutions or biological systems, making it useful in various research applications. 1-Hydroxypyridine-2-thione zinc salt′s mechanism of action involves the formation of coordination bonds with metal ions, leading to the formation of stable complexes. This chelating property enables the compound to sequester metal ions, preventing their participation in chemical reactions or biological processes.
1-Hydroxypyridine-2-thione zinc salt (CAS 13463-41-7) References
- Microbial inhibitors for U.S. EPA drinking water methods for the determination of organic compounds. | Winslow, SD., et al. 2001. Environ Sci Technol. 35: 4103-10. PMID: 11686373
- Gold complexes inhibit mitochondrial thioredoxin reductase: consequences on mitochondrial functions. | Rigobello, MP., et al. 2004. J Inorg Biochem. 98: 1634-41. PMID: 15458826
- Pannexin-1-dependent caspase-1 activation and secretion of IL-1beta is regulated by zinc. | Brough, D., et al. 2009. Eur J Immunol. 39: 352-8. PMID: 19130485
- New anti-tuberculosis agents amongst known drugs. | Lougheed, KE., et al. 2009. Tuberculosis (Edinb). 89: 364-70. PMID: 19699151
- Cytosolic acidification and intracellular zinc release in hippocampal neurons. | Kiedrowski, L. 2012. J Neurochem. 121: 438-50. PMID: 22339672
- Zinc depletion regulates the processing and secretion of IL-1β. | Summersgill, H., et al. 2014. Cell Death Dis. 5: e1040. PMID: 24481454
- Proton-dependent zinc release from intracellular ligands. | Kiedrowski, L. 2014. J Neurochem. 130: 87-96. PMID: 24606401
- Zinc Binding to MG53 Protein Facilitates Repair of Injury to Cell Membranes. | Cai, C., et al. 2015. J Biol Chem. 290: 13830-9. PMID: 25869134
- Pyrithione Zn selectively inhibits hypoxia-inducible factor prolyl hydroxylase PHD3. | Na, YR., et al. 2016. Biochem Biophys Res Commun. 472: 313-8. PMID: 26940742
- Cytosolic increased labile Zn2+ contributes to arrhythmogenic action potentials in left ventricular cardiomyocytes through protein thiol oxidation and cellular ATP depletion. | Degirmenci, S., et al. 2018. J Trace Elem Med Biol. 48: 202-212. PMID: 29773183
- Regulatory mechanisms of incomplete huntingtin mRNA splicing. | Neueder, A., et al. 2018. Nat Commun. 9: 3955. PMID: 30262848
- Zinc Blockade of SOS Response Inhibits Horizontal Transfer of Antibiotic Resistance Genes in Enteric Bacteria. | Crane, JK., et al. 2018. Front Cell Infect Microbiol. 8: 410. PMID: 30519543
- Comparison of the effects of sublethal concentrations of biofoulants, copper pyrithione and zinc pyrithione on a marine mysid - A multigenerational study. | Lee, S., et al. 2023. Comp Biochem Physiol C Toxicol Pharmacol. 271: 109694. PMID: 37394131
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OR51I1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-Hydroxypyridine-2-thione zinc salt, 10 g | sc-229790 | 10 g | $61.00 | |||
1-Hydroxypyridine-2-thione zinc salt, 100 g | sc-229790A | 100 g | $364.00 | |||
1-Hydroxypyridine-2-thione zinc salt, 1 kg | sc-229790B | 1 kg | $1457.00 |