Molecular structure of 1-Hydroxypyrene, CAS Number: 5315-79-7
1-Hydroxypyrene (CAS 5315-79-7)
Alternate Names:
1-Pyrenol; 1-Hydroxypyrene; 3-Hydroxypyrene
Application:
1-Hydroxypyrene is a metabolite
CAS Number:
5315-79-7
Molecular Weight:
218.25
Molecular Formula:
C16H10O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
1-Hydroxypyrene is a metabolite of pyrene, a polycyclic aromatic hydrocarbon (PAH) that is found in coal tar, coal-derived products, and the incomplete combustion of organic matter. Its presence in human urine is considered a biomarker for exposure to PAHs. PAHs, including pyrene, are environmental pollutants that can have various sources, such as industrial processes, vehicular exhaust, cigarette smoke, and the burning of coal and wood. The measurement of 1-hydroxypyrene levels allows for the evaluation of the internal dose of PAHs that individuals are exposed to, providing valuable information for risk assessment and management strategies aimed at reducing exposure in affected populations.
1-Hydroxypyrene (CAS 5315-79-7) References
- 1-Hydroxypyrene as a biomarker of PAH exposure in the marine polychaete Nereis diversicolor. | Tairova, ZM., et al. 2009. Mar Environ Res. 67: 38-46. PMID: 19058843
- Urinary 1-hydroxypyrene and PAH exposure in 4-year-old Spanish children. | Freire, C., et al. 2009. Sci Total Environ. 407: 1562-9. PMID: 19095289
- 1-Hydroxypyrene and 3-hydroxybenzo[a]pyrene as biomarkers of exposure to PAH in various environmental exposure situations. | Leroyer, A., et al. 2010. Sci Total Environ. 408: 1166-73. PMID: 19922977
- 1-Hydroxypyrene--a biochemical marker for PAH pollution assessment of aquatic ecosystem. | Blahova, J., et al. 2010. Sensors (Basel). 10: 203-17. PMID: 22315535
- 1-Hydroxypyrene and oxidative stress marker levels among painting workers and office workers at shipyard. | Kho, Y., et al. 2015. Int Arch Occup Environ Health. 88: 297-303. PMID: 24996633
- Oxidation of pyrene, 1-hydroxypyrene, 1-nitropyrene and 1-acetylpyrene by human cytochrome P450 2A13. | Shimada, T., et al. 2016. Xenobiotica. 46: 211-24. PMID: 26247835
- Levels of 1-hydroxypyrene in urine of people living in an oil producing region of the Andean Amazon (Ecuador and Peru). | Webb, J., et al. 2018. Int Arch Occup Environ Health. 91: 105-115. PMID: 28939924
- Urinary 1-hydroxypyrene and Skin Contamination in Firefighters Deployed to the Fort McMurray Fire. | Cherry, N., et al. 2019. Ann Work Expo Health. 63: 448-458. PMID: 30753267
- Measurement of urinary 1-aminopyrene and 1-hydroxypyrene as biomarkers of exposure to diesel particulate matter in gold miners. | Du, M., et al. 2019. Sci Total Environ. 685: 723-728. PMID: 31234134
- Assay of 1-hydroxypyrene via aggregation-induced quenching of the fluorescence of protamine-modified gold nanoclusters and 9-hydroxyphenanthrene-based sensitization. | Xue, JH., et al. 2019. Mikrochim Acta. 186: 700. PMID: 31617023
- 1-Hydroxypyrene mediates renal fibrosis through aryl hydrocarbon receptor signalling pathway. | Miao, H., et al. 2022. Br J Pharmacol. 179: 103-124. PMID: 34625952
- Unearth the Luminescence Potential of Metal-Organic Frameworks: Adopting a Feasible Strategy to Fabricate One Ratiometric Fluorescence Sensor for Monitoring Both 1-Hydroxypyrene and Cu2. | Jin, Y., et al. 2022. Inorg Chem. 61: 1349-1359. PMID: 34995465
- Application of a novel nylon needle filter-based solid-phase extraction device to determination of 1-hydroxypyrene in urine. | Yue, SW., et al. 2022. J Sep Sci. 45: 1262-1272. PMID: 35029014
- Bifunctional 1-Hydroxypyrene Photocatalyst for Hydrodesulfurization via Reductive C(Aryl)-S Bond Cleavage. | Wu, D., et al. 2023. Org Lett.. PMID: 37114776
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-Hydroxypyrene, 100 mg | sc-206169 | 100 mg | $406.00 |