Date published: 2025-10-13

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1-(Hydroxymethyl)-5,5-dimethylhydantoin (CAS 116-25-6)

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Alternate Names:
5,5-Dimethyl-1-(hydroxymethyl)hydantoin
CAS Number:
116-25-6
Molecular Weight:
158.16
Molecular Formula:
C6H10N2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-(Hydroxymethyl)-5,5-dimethylhydantoin is a benzimidazole derivative that has antimicrobial properties, making it an effective agent in combating bacterial and fungal infections. The compound is synthesized through the reaction of benzaldehyde with hydrazine hydrochloride. In vitro studies show that 1-(Hydroxymethyl)-5,5-dimethylhydantoin forms a complex known as silver 1-(Hydroxymethyl)-5,5-dimethylhydantoin when exposed to silver ions. This complex exerts its antimicrobial activity by disrupting the cell membranes of bacteria and fungi. To ensure the purity of 1-(Hydroxymethyl)-5,5-dimethylhydantoin, analytical techniques such as chloride content measurement and particle size distribution analysis can be used.


1-(Hydroxymethyl)-5,5-dimethylhydantoin (CAS 116-25-6) References

  1. Quantification of 1,3-dimethylol-5,5-dimethylhydantoin and its decomposition products in cosmetics by high-performance liquid chromatography.  |  Asada, A., et al. 2012. J Pharm Biomed Anal. 67-68: 163-8. PMID: 22633837
  2. Clear polyurethane coatings with excellent virucidal properties: Preparation, characterization and rapid inactivation of human coronaviruses 229E and SARS-CoV-2.  |  Salgado, C., et al. 2023. Appl Mater Today. 32: 101828. PMID: 37317691

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-(Hydroxymethyl)-5,5-dimethylhydantoin, 25 g

sc-258513
25 g
$32.00

1-(Hydroxymethyl)-5,5-dimethylhydantoin, 100 g

sc-258513A
100 g
$111.00