1-Hydroxy-7-azabenzotriazole 1M DMA solution (CAS 39968-33-7)
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1-Hydroxy-7-azabenzotriazole 1M DMA solution is a reagent used in the field of peptide synthesis. It acts as a coupling reagent that facilitates the formation of peptide bonds between amino acid units. The 1M concentration in DMA (N,N-Dimethylacetamide) provides a ready-to-use solution that simplifies the process of activating carboxyl groups during peptide chain elongation. Researchers value this solution for its efficiency in promoting amide bond formation with minimal racemization, which is for obtaining peptides with the desired chirality. Additionally, 1-Hydroxy-7-azabenzotriazole, often abbreviated as HOAt, enhances the reaction rates of coupling, making it a preferred choice in solid-phase peptide synthesis protocols. This compound is also studied in relation to its role in the synthesis of complex organic molecules beyond peptides, such as cyclic compounds and various heterocycles.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-Hydroxy-7-azabenzotriazole 1M DMA solution, 25 ml | sc-507175 | 25 ml | $104.00 | |||
1-Hydroxy-7-azabenzotriazole 1M DMA solution, 250 ml | sc-507175B | 250 ml | $947.00 | |||
1-Hydroxy-7-azabenzotriazole 1M DMA solution, 100 ml | sc-507175A | 100 ml | $385.00 |