Molecular structure of 1-Hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine hydrochloride, CAS Number: 3637-11-4
1-Hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine hydrochloride (CAS 3637-11-4)
Alternate Names:
TEMPONE-H hydrochloride; 1-Hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine HCl
Application:
1-Hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine hydrochloride is a cell permeable spin trap for detection of superoxide radical and peroxynitrite
CAS Number:
3637-11-4
Molecular Weight:
207.70
Molecular Formula:
C9H17NO2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
1-Hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine hydrochloride is a very effective, cell permeable and non-toxic spin trap for the detection of superoxide radical and peroxynitrite.
1-Hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine hydrochloride (CAS 3637-11-4) References
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- Salidroside improves homocysteine-induced endothelial dysfunction by reducing oxidative stress. | Leung, SB., et al. 2013. Evid Based Complement Alternat Med. 2013: 679635. PMID: 23589720
- Cyclooxygenase-2-dependent oxidative stress mediates palmitate-induced impairment of endothelium-dependent relaxations in mouse arteries. | Gao, Z., et al. 2014. Biochem Pharmacol. 91: 474-82. PMID: 25149102
- Bioavailable Concentrations of Delphinidin and Its Metabolite, Gallic Acid, Induce Antioxidant Protection Associated with Increased Intracellular Glutathione in Cultured Endothelial Cells. | Goszcz, K., et al. 2017. Oxid Med Cell Longev. 2017: 9260701. PMID: 29081896
- Efficacy of low-temperature plasma-activated gas disinfection against biofilm on contaminated GI endoscope channels. | Bhatt, S., et al. 2019. Gastrointest Endosc. 89: 105-114. PMID: 30120959
- Quantification of peroxynitrite, superoxide, and peroxyl radicals by a new spin trap hydroxylamine 1-hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine. | Dikalov, S., et al. 1997. Biochem Biophys Res Commun. 230: 54-7. PMID: 9020059
- Spin trapping of superoxide radicals and peroxynitrite by 1-hydroxy-3-carboxy-pyrrolidine and 1-hydroxy-2,2,6, 6-tetramethyl-4-oxo-piperidine and the stability of corresponding nitroxyl radicals towards biological reductants. | Dikalov, S., et al. 1997. Biochem Biophys Res Commun. 231: 701-4. PMID: 9070876
- Quantification of superoxide radicals and peroxynitrite in vascular cells using oxidation of sterically hindered hydroxylamines and electron spin resonance. | Dikalov, S., et al. 1997. Nitric Oxide. 1: 423-31. PMID: 9441913
- Inactivation effects of the mist nebulized with plasma‐activated air on Pseudomonas aeruginosa through the simulated respiratory tract. | Guo, Li, et al. 2023. Plasma Processes and Polymers. 20.9: e2200204.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-Hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine hydrochloride, 10 mg | sc-202833 | 10 mg | $51.00 |