Date published: 2025-9-25

1-800-457-3801

SCBT Portrait Logo
Seach Input

1-Fluorohexane (CAS 373-14-8)

0.0(0)
Write a reviewAsk a question

Alternate Names:
Hexyl fluoride
CAS Number:
373-14-8
Molecular Weight:
104.17
Molecular Formula:
CH3(CH2)5F
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

1-Fluorohexane is an organofluorine compound that finds its use primarily in the field of organic chemistry as a reagent or solvent. Its fluorinated alkane structure is of interest in studies of hydrophobic interactions and membrane dynamics due to the presence of the fluorocarbon chain. Researchers may employ it in the synthesis of more complex fluorinated organic molecules, taking advantage of the reactivity imparted by the fluorine atom at the terminal position. This reactivity is also pivotal in studies of reaction mechanisms where fluorine′s effects on electron distribution and bond strength are investigated. Additionally, 1-fluorohexane serves as a model compound in physical chemistry for understanding the physicochemical properties of fluorinated hydrocarbons, which include their phase behavior, solubility, and thermal stability.


1-Fluorohexane (CAS 373-14-8) References

  1. Aliphatic and aromatic carbon-fluorine bond activation with Cp*(2)ZrH(2): mechanisms of hydrodefluorination.  |  Kraft, BM., et al. 2001. J Am Chem Soc. 123: 10973-9. PMID: 11686701
  2. Ultra-high vacuum scanning tunneling microscopy and theoretical studies of 1-halohexane monolayers on graphite.  |  Müller, T., et al. 2005. Proc Natl Acad Sci U S A. 102: 5315-22. PMID: 15758073
  3. Role of binding energy in Feshbach-resonant positron-molecule annihilation.  |  Young, JA. and Surko, CM. 2007. Phys Rev Lett. 99: 133201. PMID: 17930585
  4. Adsorption energy of nano- and microparticles at liquid-liquid interfaces.  |  Du, K., et al. 2010. Langmuir. 26: 12518-22. PMID: 20593775
  5. Oxidative addition of carbon-fluorine and carbon-oxygen bonds to Al(I).  |  Crimmin, MR., et al. 2015. Chem Commun (Camb). 51: 15994-6. PMID: 26389715
  6. Use of Trifluoromethyl Groups for Catalytic Benzylation and Alkylation with Subsequent Hydrodefluorination.  |  Zhu, J., et al. 2016. Angew Chem Int Ed Engl. 55: 1417-21. PMID: 26663711
  7. Discovery of Novel Haloalkane Dehalogenase Inhibitors.  |  Buryska, T., et al. 2016. Appl Environ Microbiol. 82: 1958-1965. PMID: 26773086
  8. Chemical transferability of functional groups follows from the nearsightedness of electronic matter.  |  Fias, S., et al. 2017. Proc Natl Acad Sci U S A. 114: 11633-11638. PMID: 29078266
  9. Reactions of Fluoroalkanes with Mg-Mg Bonds: Scope, sp3 C-F/sp2 C-F Coupling and Mechanism.  |  Coates, G., et al. 2018. Chemistry. 24: 16282-16286. PMID: 30207410
  10. Dihydridoboranes: Selective Reagents for Hydroboration and Hydrodefluorination.  |  Phillips, NA., et al. 2019. Org Lett. 21: 7289-7293. PMID: 31497960
  11. A comparative study of the hepatotoxicity of 1-fluoropentane and 1-fluorohexane.  |  Nhachi, CF. and Chikuni, O. 1988. Food Chem Toxicol. 26: 705-13. PMID: 3198037
  12. Defluoroalkylation of sp3 C-F Bonds of Industrially Relevant Hydrofluoroolefins.  |  Phillips, NA., et al. 2020. Chemistry. 26: 5365-5368. PMID: 32039506
  13. Pseudomonas sp. Strain 273 Degrades Fluorinated Alkanes.  |  Xie, Y., et al. 2020. Environ Sci Technol. 54: 14994-15003. PMID: 33190477

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Fluorohexane, 10 g

sc-258745
10 g
$312.00

1-Fluorohexane, 25 g

sc-258745A
25 g
$939.00