Date published: 2026-4-24

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1-Fluoroadamantane (CAS 768-92-3)

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Alternate Names:
1-Adamantyl Fluoride
CAS Number:
768-92-3
Molecular Weight:
154.23
Molecular Formula:
C10H15F
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Fluoroadamantane is a halogenated hydrocarbon that is often utilized in research applications for its properties as a building block in organic synthesis. Due to its rigid, cage-like structure, 1-Fluoroadamantane is explored in the study of host-guest chemistry, where its ability to interact with various molecules can shed light on molecular recognition processes. It also serves as a model compound in the field of materials science, particularly in the design of new polymers and nanomaterials, where the influence of its sterically hindered framework on polymer characteristics is of interest. In addition, 1-Fluoroadamantane is involved in mechanistic studies in physical chemistry, including investigations into reaction kinetics and the stability of carbon-fluorine bonds, which are relevant in the synthesis of more complex fluorinated compounds.


1-Fluoroadamantane (CAS 768-92-3) References

  1. Conversion of a (sp3)C-F bond of alkyl fluorides to (sp3)C-X (X = Cl, C, H, O, S, Se, Te, N) bonds using organoaluminium reagents.  |  Terao, J., et al. 2007. Chem Commun (Camb). 855-7. PMID: 17308654
  2. Protolytic defluorination of trifluoromethyl-substituted arenes.  |  Kethe, A., et al. 2011. Org Biomol Chem. 9: 4545-9. PMID: 21547324
  3. Application of the Grunwald-Winstein Equations to Studies of Solvolytic Reactions of Chloroformate and Fluoroformate Esters.  |  D'Souza, MJ. and Kevill, DN. 2013. Recent Res Dev Org Chem. 13: 1-38. PMID: 25364780
  4. Subcomponent Exchange Transforms an FeII4L4 Cage from High- to Low-Spin, Switching Guest Release in a Two-Cage System.  |  McConnell, AJ., et al. 2017. J Am Chem Soc. 139: 6294-6297. PMID: 28426930
  5. Reactions of Fluoroalkanes with Mg-Mg Bonds: Scope, sp3 C-F/sp2 C-F Coupling and Mechanism.  |  Coates, G., et al. 2018. Chemistry. 24: 16282-16286. PMID: 30207410
  6. Interactions of C-F Bonds with Hydridoboranes: Reduction, Borylation and Friedel-Crafts Alkylation.  |  Bamford, KL., et al. 2018. Chemistry. 24: 16014-16018. PMID: 30222215
  7. Bis(perchlorocatecholato)germane: Hard and Soft Lewis Superacid with Unlimited Water Stability.  |  Roth, D., et al. 2020. Angew Chem Int Ed Engl. 59: 20930-20934. PMID: 32776679
  8. Isolable Silicon-Based Polycations with Lewis Superacidity.  |  Hermannsdorfer, A. and Driess, M. 2020. Angew Chem Int Ed Engl. 59: 23132-23136. PMID: 32935903
  9. Ga+-catalyzed hydrosilylation? About the surprising system Ga+/HSiR3/olefin, proof of oxidation with subvalent Ga+ and silylium catalysis with perfluoroalkoxyaluminate anions.  |  Barthélemy, A., et al. 2022. Chem Sci. 13: 439-453. PMID: 35126976
  10. Ultrasonic study of 1-X adamantane (X = F, Cl, Br) compounds at high pressure and at order-disorder transitions.  |  Gromnitskaya, EL., et al. 2022. Phys Chem Chem Phys. 24: 18022-18027. PMID: 35861225
  11. Tris(ortho-carboranyl)borane: An Isolable, Halogen-Free, Lewis Superacid.  |  Akram, MO., et al. 2022. Angew Chem Int Ed Engl. 61: e202212073. PMID: 36135949
  12. Unraveling the Complex Solid-State Phase Transition Behavior of 1-Iodoadamantane, a Material for Which Ostensibly Identical Crystals Undergo Different Transformation Pathways.  |  Al Rahal, O., et al. 2023. Cryst Growth Des. 23: 3820-3833. PMID: 37159655
  13. 'Sandwich' Diimine-Copper Catalyzed Trifluoroethylation and Pentafluoropropylation of Unactivated C(sp3)-H Bonds by Carbene Insertion.  |  Le, TV., et al. 2023. Chemistry. e202301672. PMID: 37267071

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Fluoroadamantane, 250 mg

sc-485408
250 mg
$138.00