Date published: 2025-11-3

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1-Ethynylcyclopentanol (CAS 17356-19-3)

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Alternate Names:
Cyclopentyl ethynyl carbinol
CAS Number:
17356-19-3
Molecular Weight:
110.15
Molecular Formula:
C7H10O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Ethynylcyclopentanol serves as a chemical building block in organic synthesis. It acts as a substrate in various reactions, including Sonogashira coupling, which involves the formation of carbon-carbon bonds. 1-Ethynylcyclopentanol participates in the formation of new carbon-carbon bonds through its alkyne functional group, allowing for the creation of complex organic molecules. In this capacity, 1-Ethynylcyclopentanol plays a role in the development of novel materials and compounds with potential applications in various fields. At the molecular level, it undergoes reactions with other reagents to facilitate the construction of diverse molecular structures. Its mechanism of action involves participating in chemical transformations that lead to the synthesis of diverse organic compounds, thereby expanding the repertoire of available molecules for further study and potential application in various experimental applications.


1-Ethynylcyclopentanol (CAS 17356-19-3) References

  1. Nickel-catalyzed addition of P(O)-H bonds to propargyl alcohols: one-pot generation of phosphinoyl 1,3-butadienes.  |  Han, LB., et al. 2005. Org Lett. 7: 2909-11. PMID: 15987167
  2. Electrospray ionization mass spectrometric characterization of key Te(IV) cationic intermediates for the addition of TeCl4 to alkynes.  |  Santos, LS., et al. 2007. Rapid Commun Mass Spectrom. 21: 1479-84. PMID: 17394126
  3. Luminescent Au(I)/Cu(I) alkynyl clusters with an ethynyl steroid and related aliphatic ligands: an octanuclear Au4Cu4 cluster and luminescence polymorphism in Au3Cu2 clusters.  |  Manbeck, GF., et al. 2010. J Am Chem Soc. 132: 12307-18. PMID: 20704268
  4. Modulation of metallophilic bonds: solvent-induced isomerization and luminescence vapochromism of a polymorphic Au-Cu cluster.  |  Koshevoy, IO., et al. 2012. J Am Chem Soc. 134: 6564-7. PMID: 22469012
  5. Rapid Access to 2-Methylene Tetrahydrofurans and γ-Lactones: A Tandem Four-Step Process.  |  Liang, R., et al. 2016. Angew Chem Int Ed Engl. 55: 2587-91. PMID: 26797825
  6. Gas-Phase Optical Detection of 3-Ethynylcyclopentenyl: A Resonance-Stabilized C7H7 Radical with an Embedded 1-Vinylpropargyl Chromophore.  |  Reilly, NJ., et al. 2020. J Am Chem Soc. 142: 10400-10411. PMID: 32396343
  7. Platinum-acetylene complexes. II. Monosubstituted hydroxyacetylenes  |  John Henry Nelson, H. B. Jonassen, and D. M. Roundhill, et al. 1969. Inorg. Chem. 8: 2591–2596.
  8. Reactions of palladium(0) phosphine complexes with terminal.alpha.-hydroxyacetylenes  |  John H. Nelson, Allen W. Verstuyft, James D. Kelly, and Hans B. Jonassen, et al. 1974. Inorg. Chem. 13: 27–33.
  9. Diacetone glucose architecture as a chirality template I. Crucial effects of the intramolecular oxygens upon the LiAlH4 reduction of the propargyl alcohol of 3-C-ethynyl-1,2:5,6-di-O-isopropylidene-α-D-allofuranose derivatives  |  Katsumi Kakinuma ∗, Toshihiro Matsuzawa, Tadashi Eguchi. 1991. Tetrahedron. 47: 6975-6982.
  10. Synthesis, characterization and biological activity of (Z)-1-[2]-1-cyclopentanol and their arylhalostannyl derivatives  |  Hui Cong Dai 1, QiHua Ying 1, Xiao Hong Wang 1, Su Mei Yue 1, Hua De Pan 1, Xi Chen 2. 1998. Polyhedron. 17: 2503-2509.
  11. Synthesis and molecular structure of hexaruthenium clusters containing unsaturated ring systems derived from 1-ethynylcyclopentanol, 1-ethynylcycloheptanol and 1-ethynylcyclooctano  |  Cindy Sze-Wai Lau, Wing-Tak Wong. 1999. Journal of Organometallic Chemistry. 589: 198-212.
  12. Luminescent Au3Ag6 heterononanuclear complex of 1-ethynylcyclopentanol  |  Zai-Lai Xie, Qiao-Hua Wei, Li-Yi Zhang, Zhong-Ning Chen. 2007. Inorganic Chemistry Communications. 10: 1206-1209.
  13. Air-induced double addition of P(O)–H bonds to alkynes: a clean and practical method for the preparation of 1,2-bisphosphorylethanes  |  Haiqing Guo,a Aya Yoshimura,*a Tieqiao Chen,a Yuta Sagab and Li-Biao Han *a. 2017. Green Chem. 19: 1502-1506.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Ethynylcyclopentanol, 5 g

sc-224673
5 g
$81.00