Date published: 2026-4-20

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1-ethylpiperidin-4-ol (CAS 3518-83-0)

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Alternate Names:
1-Ethyl-4-hydroxypiperidine
CAS Number:
3518-83-0
Molecular Weight:
129.2
Molecular Formula:
C7H15NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-ethylpiperidin-4-ol, serves as a building block for the synthesis of more complex molecules, particularly those with potential utility in materials science and as ligands in catalytic systems. It is also utilized in producing biologically active compounds and forming polymers such as polyurethanes and polycarbonates. As a nucleophilic reagent, 1-ethylpiperidin-4-ol can engage with electrophilic species like carbonyl compounds in reactions facilitated by bases such as sodium hydroxide.


1-ethylpiperidin-4-ol (CAS 3518-83-0) References

  1. Development of an Expedient Process for the Multi-Kilogram Synthesis of Chk1 Inhibitor GDC-0425  |  Andreas Stumpf*†, Zhigang Ken Cheng†, Brian Wong†, Mark Reynolds†, Remy Angelaud†, James Girotti‡, Alan Deese‡, Christine Gu‡, and Lewis Gazzard§. 2015,. Org. Process Res. Dev. 19, 6,: 661–672.
  2. Discovery of a class of diheteroaromatic amines as orally bioavailable CDK1/4/6 inhibitors  |  Y Fu, S Tang, Y Su, X Lan, Y Ye, C Zha, L Li… - Bioorganic & Medicinal …, 2017 - Elsevier. 1 December 2017,. Bioorganic & Medicinal Chemistry Letters. Volume 27, Issue 23,: Pages 5332-5336.
  3. Discovery and biological evaluation of 1-{2,7-diazaspiro[3.5]nonan-2-yl}prop-2-en-1-one derivatives as covalent inhibitors of KRAS G12C with favorable metabolic stability and anti-tumor activity  |  T Imaizumi, M Akaiwa, T Abe, T Nigawara… - Bioorganic & Medicinal …, 2022 - Elsevier. 1 October 2022,. Bioorganic & Medicinal Chemistry. Volume 71,: 116949.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-ethylpiperidin-4-ol, 1 g

sc-333961
1 g
$150.00

1-ethylpiperidin-4-ol, 5 g

sc-333961A
5 g
$312.00