Molecular structure of 1-Ethyl-2,3,3-trimethylindolenium-5-sulfate, CAS Number: 146368-07-2
1-Ethyl-2,3,3-trimethylindolenium-5-sulfate (CAS 146368-07-2)
Alternate Names:
1-Ethyl-2,3,3-trimethyl-5-sulfo-3H-indolium Inner Salt
CAS Number:
146368-07-2
Purity:
≥95%
Molecular Weight:
267.34
Molecular Formula:
C13H17NO3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
Safety Information
SDS & Certificate of Analysis
1-Ethyl-2,3,3-trimethylindolenium-5-sulfate aslo know as 1-Ethyl-2,3,3-trimethyl-3H-indol-1-ium-5-sulfonate,or EMTI-5S, functions as an inhibitor of thymidylate synthase, an enzyme essential for thymidine synthesis in DNA. 1-Ethyl-2,3,3-trimethylindolenium-5-sulfate binds to the active site of thymidylate synthase, hindering its activity and impeding thymidine production. This inhibition leads to the accumulation of unmetabolized thymidine, ultimately resulting in cell death. Additionally, 1-Ethyl-2,3,3-trimethylindolenium-5-sulfate has demonstrated inhibitory effects on other enzymes such as proteases, phosphatases, and kinases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-Ethyl-2,3,3-trimethylindolenium-5-sulfate, 250 mg | sc-213327 | 250 mg | $262.00 |