Date published: 2025-11-1

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1-Decanoyl-rac-glycerol (CAS 26402-22-2)

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Alternate Names:
Monocaprin
Application:
1-Decanoyl-rac-glycerol is active against bacteria such as candida albicans and campylobacter
CAS Number:
26402-22-2
Purity:
≥96%
Molecular Weight:
246.34
Molecular Formula:
C13H26O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Decanoyl-rac-glycerol, commonly known as monoacylglycerol (MAG) with a decanoyl fatty acid chain, is a molecular entity extensively utilized in research, particularly in the study of lipid metabolism and the structure and function of biological membranes. This molecule, featuring a glycerol backbone esterified at one of its hydroxyl groups with a decanoic acid (capric acid), serves as a simplified model to understand the interactions and dynamics of lipids in cellular environments. In biochemical research, 1-Decanoyl-rac-glycerol is instrumental in examining the role of monoacylglycerols in the assembly and stability of lipid bilayers and micelles. Its behavior in aqueous solutions provides insights into the physicochemical properties of lipids, such as critical micelle concentration and the thermodynamics of micelle formation. Furthermore, studies involving 1-Decanoyl-rac-glycerol have helped explain mechanisms of lipid signaling and the modulation of membrane-bound enzymes and receptor activities. In nutritional sciences, it aids in the exploration of how different fatty acid chains affect the physical properties of fats and their interactions within food matrices, thereby influencing food texture and stability. By studying such monoacylglycerols, researchers can better understand lipid behavior in non-biological systems, contributing to advancements in materials science, such as in the development of bio-compatible lubricants and targeted delivery systems in non-medical applications.


1-Decanoyl-rac-glycerol (CAS 26402-22-2) References

  1. Optimized reverse micelle surfactant system for high-resolution NMR spectroscopy of encapsulated proteins and nucleic acids dissolved in low viscosity fluids.  |  Dodevski, I., et al. 2014. J Am Chem Soc. 136: 3465-74. PMID: 24495164
  2. Robust hydrolysis of prostaglandin glycerol esters by human monoacylglycerol lipase (MAGL).  |  Savinainen, JR., et al. 2014. Mol Pharmacol. 86: 522-35. PMID: 25140003
  3. Novel LC/MS/MS and High-Throughput Mass Spectrometric Assays for Monoacylglycerol Acyltransferase Inhibitors.  |  Qi, J., et al. 2017. SLAS Discov. 22: 433-439. PMID: 28328322
  4. Giant vesicles from rehydrated crude mixtures containing unexpected mixtures of amphiphiles formed under plausibly prebiotic conditions.  |  Fiore, M., et al. 2017. Org Biomol Chem. 15: 4231-4240. PMID: 28466946
  5. Identification of acetylated diether lipids in halophilic Archaea.  |  Kropp, C., et al. 2022. Microbiologyopen. 11: e1299. PMID: 35765181
  6. Characterization of Reverse Micelle Surfactant Mixture for Biophysical and Biomedical Applications[J].  |  Mawson C, Berg J, Work H. 2018. Biophysical Journal. 114(3): 566a.
  7. Reverse micelle surfactant system comprising the 1-decanoyl-rac-glycerol and the Lauryldimethylamine-N-oxide: Structure and dynamics of confined water[J].  |  Bazaziyan B, Bozorgmehr M R, Momen-Heravi M. 2019. Russian Journal of Physical Chemistry A. 93: 1122-1127.
  8. Flavodoxin in a binary surfactant system consisting of the nonionic 1-decanoyl-rac-glycerol and the zwitterionic lauryldimethylamine-N-oxide: Molecular dynamics simulation approach[J].  |  Bazaziyan B, Bozorgmehr M R, Momen-Heravi M. 2020. Papers in physics,. 12: 120004-120004.
  9. Effective nanoparticulate-type encapsulation delivery system for hydrophilic proteins and peptides[J].  |  Massignan F, Gyulai G, Bősze S. 2024. Express Polymer Letters. 18(1).
  10. Different Substrate Selectivity and Product Patterns of Immobilized Thermophilic Lipases from Geobacillus stearothermophilus, Anoxybacillus flavithermus, and Thermomyces lanuginosus for Glyceryl Decanoate Synthesis[J].  |  Najm T A, Walsh M K, Park N. 2024. ChemEngineering. 8(1): 12.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Decanoyl-rac-glycerol, 100 mg

sc-213324
100 mg
$56.00

1-Decanoyl-rac-glycerol, 1 g

sc-213324A
1 g
$279.00