Date published: 2026-1-21

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1-Cyclopropylmethanamine (CAS 2516-47-4)

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Alternate Names:
(Aminomethyl)cyclopropane
CAS Number:
2516-47-4
Molecular Weight:
71.12
Molecular Formula:
C4H9N
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Cyclopropylmethanamine is a chemical compound that is frequently used as a building block in organic synthesis. Its presence in a variety of synthetic pathways allows researchers to create more complex molecules. The cyclopropyl group in 1-Cyclopropylmethanamine is known to impart stability to the resulting compounds and can influence the biological activity of the synthesized molecules. In studies of reaction mechanisms, this compound is often employed to understand the behavior of cyclopropyl-containing amines under different conditions. Additionally, 1-Cyclopropylmethanamine is used in the synthesis of ligands for transition metal catalysis, which is for the development of new catalytic methods in organic chemistry.


1-Cyclopropylmethanamine (CAS 2516-47-4) References

  1. Tetrahydrochromenoimidazoles as potassium-competitive acid blockers (P-CABs): structure-activity relationship of their antisecretory properties and their affinity toward the hERG channel.  |  Palmer, AM., et al. 2010. J Med Chem. 53: 3645-74. PMID: 20380432
  2. Design and in vitro activities of N-alkyl-N-[(8-R-2,2-dimethyl-2H-chromen-6-yl)methyl]heteroarylsulfonamides, novel, small-molecule hypoxia inducible factor-1 pathway inhibitors and anticancer agents.  |  Mun, J., et al. 2012. J Med Chem. 55: 6738-50. PMID: 22746274
  3. Discovery of highly potent and selective small molecule ADAMTS-5 inhibitors that inhibit human cartilage degradation via encoded library technology (ELT).  |  Deng, H., et al. 2012. J Med Chem. 55: 7061-79. PMID: 22891645
  4. Identification of a Benzimidazolecarboxylic Acid Derivative (BAY 1316957) as a Potent and Selective Human Prostaglandin E2 Receptor Subtype 4 (hEP4-R) Antagonist for the Treatment of Endometriosis.  |  Bäurle, S., et al. 2019. J Med Chem. 62: 2541-2563. PMID: 30707023
  5. Inhibitors Designed for Presenilin 1 by Means of Aspartic Acid Activation. Preliminary Communication  |   and Gregor Larbig, Andrea Zall, Boris Schmidt. 2004. Helvetica chimica acta. 87: 2334-2340.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Cyclopropylmethanamine, 5 g

sc-297840
5 g
$225.00

1-Cyclopropylmethanamine, 25 g

sc-297840A
25 g
$719.00